Introducing
Dr Izanne Roos
Hello, I’m Izanne, a Neurologist and Ph.D. candidate (Multiple Sclerosis) in the Clinical Outcomes Research (CORe) Unit.
a little bit about me
I am a Ph.D. student in the CORe Unit at the University of Melbourne and a clinical fellow in the Multiple Sclerosis & Neuroimmunology Service at the Royal Melbourne Hospital.
I completed my training in neurology at the University of Kwazulu Natal, South Africa in 2015. Under the supervision of A/Prof Tomas Kalincik, Dr Charles Malpas and Prof Helmut Butzkueven, I am currently developing my analytical skills in Multiple Sclerosis related outcomes based research. This opportunity has been made possible through funding from the University of Melbourne, Multiple Sclerosis International Federation (MSIF) and Biogen.
Publications
Effects of High- and Low-Efficacy Therapy in Secondary Progressive Multiple Sclerosis
Izanne Roos, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Havrdova, Guillermo Izquierdo, Sara Eichau Madueño, Francesco Patti, Gilles Edan, Marc Debouverie, Jean Pelletier, Serkan Ozakbas, Maria Pia Amato, Pierre Clavelou, Pierre Grammond, Cavit Boz, Katherine Buzzard, Olga Skibina, Jonathan Ciron, Oliver Gerlach, Francois Grand'Maison, Jeannette Lechner-Scott, Charles Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik, MSBase and OFSEP Study Groups
Neurology. 2021 Aug 31;97(9):e869-e880. doi: 10.1212/WNL.0000000000012354. Epub 2021 Jun 30.
Predicting Infection Risk in Multiple Sclerosis Patients Treated with Ocrelizumab: A Retrospective Cohort Study
Nabil Seery, Sifat Sharmin, Vivien Li, Ai-Lan Nguyen, Claire Meaton, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Mark P Marriott, Katherine A Buzzard, Izanne Roos, Chris Dwyer, Josephine Baker, Lisa Taylor, Kymble Spriggs, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
CNS Drugs. 2021 Aug;35(8):907-918. doi: 10.1007/s40263-021-00810-3. Epub 2021 Apr 13.
Determinants of therapeutic lag in multiple sclerosis
Izanne Roos, Emmanuelle Leray, Federico Frascoli, Romain Casey, J William L Brown, Dana Horakova, Eva Kubala Havrdova, Marc Debouverie, Maria Trojano, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Gilles Edan, Alexandre Prat, Marc Girard, Pierre Duquette, Marco Onofrj, Alessandra Lugaresi, Pierre Grammond, Jonathan Ciron, Aurélie Ruet, Serkan Ozakbas, Jérôme De Seze, Céline Louapre, Hélène Zephir, Maria José Sá, Patrizia Sola, Diana Ferraro, Pierre Labauge, Gilles Defer, Roberto Bergamaschi, Christine Lebrun-Frenay, Cavit Boz, Elisabetta Cartechini, Thibault Moreau, David Laplaud, Jeannette Lechner-Scott, Francois Grand'Maison, Oliver Gerlach, Murat Terzi, Franco Granella, Raed Alroughani, Gerardo Iuliano, Vincent Van Pesch, Bart Van Wijmeersch, Daniele LA Spitaleri, Aysun Soysal, Eric Berger, Julie Prevost, Eduardo Aguera-Morales, Pamela McCombe, Tamara Castillo Triviño, Pierre Clavelou, Jean Pelletier, Recai Turkoglu, Bruno Stankoff, Olivier Gout, Eric Thouvenot, Olivier Heinzlef, Youssef Sidhom, Riadh Gouider, Tunde Csepany, Bertrand Bourre, Abdullatif Al Khedr, Olivier Casez, Philippe Cabre, Alexis Montcuquet, Abir Wahab, Jean-Philippe Camdessanche, Aude Maurousset, Ivania Patry, Karolina Hankiewicz, Corinne Pottier, Nicolas Maubeuge, Céline Labeyrie, Chantal Nifle, Alasdair Coles, Charles B Malpas, Sandra Vukusic, Helmut Butzkueven, Tomas Kalincik
Mult Scler. 2021 Oct;27(12):1838-1851. doi: 10.1177/1352458520981300. Epub 2021 Jan 11.
Evaluating the perspective of patients with MS and related conditions on their DMT in relation to the COVID-19 pandemic in one MS centre in Australia
Nabil Seery, Vivien Li, Ai-Lan Nguyen, Izanne Roos, Katherine A Buzzard, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Chris Dwyer, Hasini Fernandoa Lisa Taylor, Josephine Baker, Mark P Marriott, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
Mult Scler Relat Disord. 2020 Nov;46:102516. doi: 10.1016/j.msard.2020.102516. Epub 2020 Sep 16.
Delay from treatment start to full effect of immunotherapies for multiple sclerosis
Izanne Roos, Emmanuelle Leray, Federico Frascoli, Romain Casey, J William L Brown, Dana Horakova, Eva K Havrdova, Maria Trojano, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Grammond, Patrizia Sola, Diana Ferraro, Serkan Ozakbas, Roberto Bergamaschi, Maria José Sá, Elisabetta Cartechini, Cavit Boz, Franco Granella, Raymond Hupperts, Murat Terzi, Jeannette Lechner-Scott, Daniele Spitaleri, Vincent Van Pesch, Aysun Soysal, Javier Olascoaga, Julie Prevost, Eduardo Aguera-Morales, Mark Slee, Tunde Csepany, Recai Turkoglu, Youssef Sidhom, Riadh Gouider, Bart Van Wijmeersch, Pamela McCombe, Richard Macdonell, Alasdair Coles, Charles B Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik, MSBase, OFSEP investigators
Brain. 2020 Sep 1;143(9):2742-2756. doi: 10.1093/brain/awaa231.
Early clinical markers of aggressive multiple sclerosis
Charles B Malpas, Ali Manouchehrinia, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Maria Trojano, Guillermo Izquierdo, Sara Eichau, Roberto Bergamaschi, Patrizia Sola, Diana Ferraro, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Francois Grand'Maison, Serkan Ozakbas, Vincent Van Pesch, Franco Granella, Raymond Hupperts, Eugenio Pucci, Cavit Boz, Youssef Sidhom, Riadh Gouider, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Freek Verheul, Rana Karabudak, Recai Turkoglu, Cristina Ramo-Tello, Murat Terzi, Edgardo Cristiano, Mark Slee, Pamela McCombe, Richard Macdonell, Yara Fragoso, Javier Olascoaga, Ayse Altintas, Tomas Olsson, Helmut Butzkueven, Jan Hillert, Tomas Kalincik
Brain. 2020 May 1;143(5):1400-1413. doi: 10.1093/brain/awaa081.
Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures
Albert D Wang, Michelle Leong, Benjamin Johnstone, Genevieve Rayner, Tomas Kalincik, Izanne Roos, Patrick Kwan, Terence J O'Brien, Dennis Velakoulis, Charles B Malpas
Epilepsy Res. 2019 Dec;158:106234. doi: 10.1016/j.eplepsyres.2019.106234. Epub 2019 Nov 1.
Personality profiles differ between patients with epileptic seizures and patients with psychogenic non-epileptic seizures
Michelle Leong, Albert D Wang, David Trainor, Ben Johnstone, Genevieve Rayner, Tomas Kalincik, Izanne Roos, Patrick Kwan, Terence J O'Brien, Dennis Velakoulis, Charles B Malpas
Seizure. 2019 Dec;73:1-8. doi: 10.1016/j.seizure.2019.10.011. Epub 2019 Oct 17.
Posttubercular syringomyelia in HIV-infected patients: A report of 10 cases and literature review
Suzaan Marais, Izanne Roos, Ayesha Mitha, Vinod Patel, Ahmed I Bhigjee
J Neurol Sci. 2018 Dec 15;395:54-61. doi: 10.1016/j.jns.2018.09.034. Epub 2018 Sep 28.
The neuromyelitis optica presentation and the aquaporin-4 antibody in HIV-seropositive and seronegative patients in KwaZulu-Natal, South Africa
Ahmed I Bhigjee, Anandan A Moodley, Izanne Roos, Cait-Lynn Wells, Pratistadevi Ramdial, Monika Esser
South Afr J HIV Med. 2017 Jan 31;18(1):684. doi: 10.4102/sajhivmed.v18i1.684. eCollection 2017.
Spinal Tuberculosis: Clinicoradiological Findings in 274 Patients
Suzaan Marais, Izanne Roos, Ayesha Mitha, Sepelong J Mabusha, Vinod Patel, Ahmed I Bhigjee
Clin Infect Dis. 2018 Jun 18;67(1):89-98. doi: 10.1093/cid/ciy020.
Izanne Roos, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Havrdova, Guillermo Izquierdo, Sara Eichau Madueño, Francesco Patti, Gilles Edan, Marc Debouverie, Jean Pelletier, Serkan Ozakbas, Maria Pia Amato, Pierre Clavelou, Pierre Grammond, Cavit Boz, Katherine Buzzard, Olga Skibina, Jonathan Ciron, Oliver Gerlach, Francois Grand'Maison, Jeannette Lechner-Scott, Charles Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik, MSBase and OFSEP Study Groups
Neurology. 2021 Aug 31;97(9):e869-e880. doi: 10.1212/WNL.0000000000012354. Epub 2021 Jun 30.
Predicting Infection Risk in Multiple Sclerosis Patients Treated with Ocrelizumab: A Retrospective Cohort Study
Nabil Seery, Sifat Sharmin, Vivien Li, Ai-Lan Nguyen, Claire Meaton, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Mark P Marriott, Katherine A Buzzard, Izanne Roos, Chris Dwyer, Josephine Baker, Lisa Taylor, Kymble Spriggs, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
CNS Drugs. 2021 Aug;35(8):907-918. doi: 10.1007/s40263-021-00810-3. Epub 2021 Apr 13.
Determinants of therapeutic lag in multiple sclerosis
Izanne Roos, Emmanuelle Leray, Federico Frascoli, Romain Casey, J William L Brown, Dana Horakova, Eva Kubala Havrdova, Marc Debouverie, Maria Trojano, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Gilles Edan, Alexandre Prat, Marc Girard, Pierre Duquette, Marco Onofrj, Alessandra Lugaresi, Pierre Grammond, Jonathan Ciron, Aurélie Ruet, Serkan Ozakbas, Jérôme De Seze, Céline Louapre, Hélène Zephir, Maria José Sá, Patrizia Sola, Diana Ferraro, Pierre Labauge, Gilles Defer, Roberto Bergamaschi, Christine Lebrun-Frenay, Cavit Boz, Elisabetta Cartechini, Thibault Moreau, David Laplaud, Jeannette Lechner-Scott, Francois Grand'Maison, Oliver Gerlach, Murat Terzi, Franco Granella, Raed Alroughani, Gerardo Iuliano, Vincent Van Pesch, Bart Van Wijmeersch, Daniele LA Spitaleri, Aysun Soysal, Eric Berger, Julie Prevost, Eduardo Aguera-Morales, Pamela McCombe, Tamara Castillo Triviño, Pierre Clavelou, Jean Pelletier, Recai Turkoglu, Bruno Stankoff, Olivier Gout, Eric Thouvenot, Olivier Heinzlef, Youssef Sidhom, Riadh Gouider, Tunde Csepany, Bertrand Bourre, Abdullatif Al Khedr, Olivier Casez, Philippe Cabre, Alexis Montcuquet, Abir Wahab, Jean-Philippe Camdessanche, Aude Maurousset, Ivania Patry, Karolina Hankiewicz, Corinne Pottier, Nicolas Maubeuge, Céline Labeyrie, Chantal Nifle, Alasdair Coles, Charles B Malpas, Sandra Vukusic, Helmut Butzkueven, Tomas Kalincik
Mult Scler. 2021 Oct;27(12):1838-1851. doi: 10.1177/1352458520981300. Epub 2021 Jan 11.
Evaluating the perspective of patients with MS and related conditions on their DMT in relation to the COVID-19 pandemic in one MS centre in Australia
Nabil Seery, Vivien Li, Ai-Lan Nguyen, Izanne Roos, Katherine A Buzzard, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Chris Dwyer, Hasini Fernandoa Lisa Taylor, Josephine Baker, Mark P Marriott, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
Mult Scler Relat Disord. 2020 Nov;46:102516. doi: 10.1016/j.msard.2020.102516. Epub 2020 Sep 16.
Delay from treatment start to full effect of immunotherapies for multiple sclerosis
Izanne Roos, Emmanuelle Leray, Federico Frascoli, Romain Casey, J William L Brown, Dana Horakova, Eva K Havrdova, Maria Trojano, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Grammond, Patrizia Sola, Diana Ferraro, Serkan Ozakbas, Roberto Bergamaschi, Maria José Sá, Elisabetta Cartechini, Cavit Boz, Franco Granella, Raymond Hupperts, Murat Terzi, Jeannette Lechner-Scott, Daniele Spitaleri, Vincent Van Pesch, Aysun Soysal, Javier Olascoaga, Julie Prevost, Eduardo Aguera-Morales, Mark Slee, Tunde Csepany, Recai Turkoglu, Youssef Sidhom, Riadh Gouider, Bart Van Wijmeersch, Pamela McCombe, Richard Macdonell, Alasdair Coles, Charles B Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik, MSBase, OFSEP investigators
Brain. 2020 Sep 1;143(9):2742-2756. doi: 10.1093/brain/awaa231.
Early clinical markers of aggressive multiple sclerosis
Charles B Malpas, Ali Manouchehrinia, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Maria Trojano, Guillermo Izquierdo, Sara Eichau, Roberto Bergamaschi, Patrizia Sola, Diana Ferraro, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Francois Grand'Maison, Serkan Ozakbas, Vincent Van Pesch, Franco Granella, Raymond Hupperts, Eugenio Pucci, Cavit Boz, Youssef Sidhom, Riadh Gouider, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Freek Verheul, Rana Karabudak, Recai Turkoglu, Cristina Ramo-Tello, Murat Terzi, Edgardo Cristiano, Mark Slee, Pamela McCombe, Richard Macdonell, Yara Fragoso, Javier Olascoaga, Ayse Altintas, Tomas Olsson, Helmut Butzkueven, Jan Hillert, Tomas Kalincik
Brain. 2020 May 1;143(5):1400-1413. doi: 10.1093/brain/awaa081.
Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures
Albert D Wang, Michelle Leong, Benjamin Johnstone, Genevieve Rayner, Tomas Kalincik, Izanne Roos, Patrick Kwan, Terence J O'Brien, Dennis Velakoulis, Charles B Malpas
Epilepsy Res. 2019 Dec;158:106234. doi: 10.1016/j.eplepsyres.2019.106234. Epub 2019 Nov 1.
Personality profiles differ between patients with epileptic seizures and patients with psychogenic non-epileptic seizures
Michelle Leong, Albert D Wang, David Trainor, Ben Johnstone, Genevieve Rayner, Tomas Kalincik, Izanne Roos, Patrick Kwan, Terence J O'Brien, Dennis Velakoulis, Charles B Malpas
Seizure. 2019 Dec;73:1-8. doi: 10.1016/j.seizure.2019.10.011. Epub 2019 Oct 17.
Posttubercular syringomyelia in HIV-infected patients: A report of 10 cases and literature review
Suzaan Marais, Izanne Roos, Ayesha Mitha, Vinod Patel, Ahmed I Bhigjee
J Neurol Sci. 2018 Dec 15;395:54-61. doi: 10.1016/j.jns.2018.09.034. Epub 2018 Sep 28.
The neuromyelitis optica presentation and the aquaporin-4 antibody in HIV-seropositive and seronegative patients in KwaZulu-Natal, South Africa
Ahmed I Bhigjee, Anandan A Moodley, Izanne Roos, Cait-Lynn Wells, Pratistadevi Ramdial, Monika Esser
South Afr J HIV Med. 2017 Jan 31;18(1):684. doi: 10.4102/sajhivmed.v18i1.684. eCollection 2017.
Spinal Tuberculosis: Clinicoradiological Findings in 274 Patients
Suzaan Marais, Izanne Roos, Ayesha Mitha, Sepelong J Mabusha, Vinod Patel, Ahmed I Bhigjee
Clin Infect Dis. 2018 Jun 18;67(1):89-98. doi: 10.1093/cid/ciy020.