Introducing
Dr Izanne Roos
Hello, I’m Izanne, a Neurologist and postdoctoral researcher (Multiple Sclerosis) in the Clinical Outcomes Research (CORe) Unit.
a little bit about me
I am a postdoctoral researcher in the Clinical Outcomes Research Unit (CORe), University of Melbourne. My research interests involve the use of observational data to guide treatment and prognostic decisions in patients with multiple sclerosis. I am also a neurologist providing care to patients with MS at the Multiple Sclerosis and Neuroimmunology Services at The Royal Melbourne Hospital and Eastern Health.
My research is currently supported by a Multiple Sclerosis Australia Postdoctoral Fellowship, and the Trish Multiple Sclerosis Research Foundation.
Publications
Early non-disabling relapses are important predictors of disability accumulation in people with relapsing-remitting multiple sclerosis
Cyrus Daruwalla, Vahid Shaygannejad, Serkan Ozakbas, Eva Kubala Havrdova, Dana Horakova, Raed Alroughani, Cavit Boz, Francesco Patti, Marco Onofrj, Alessandra Lugaresi, Sara Eichau, Marc Girard, Alexandre Prat, Pierre Duquette, Bassem Yamout, Samia J Khoury, Seyed Aidin Sajedi, Recai Turkoglu, Ayse Altintas, Olga Skibina, Katherine Buzzard, Pierre Grammond, Rana Karabudak, Anneke van der Walt, Helmut Butzkueven, Davide Maimone, Jeannette Lechner-Scott, Aysun Soysal, Nevin John, Julie Prevost, Daniele Spitaleri, Cristina Ramo-Tello, Oliver Gerlach, Gerardo Iuliano, Matteo Foschi, Radek Ampapa, Vincent van Pesch, Michael Barnett, Nevin Shalaby, Marie D'hooghe, Jens Kuhle, Maria Jose Sa, Marzena Fabis-Pedrini, Allan Kermode, Saloua Mrabet, Riadh Gouider, Suzanne Hodgkinson, Guy Laureys, Liesbeth Van Hijfte, Richard Macdonell, Celia Oreja-Guevara, Edgardo Cristiano, Pamela McCombe, Jose Luis Sanchez-Menoyo, Bhim Singhal, Yolanda Blanco, Stella Hughes, Justin Garber, Claudio Solaro, Chris McGuigan, Bruce Taylor, Koen de Gans, Mario Habek, Abdullah Al-Asmi, Simu Mihaela, Tamara Castillo Triviño, Talal Al-Harbi, Juan Ignacio Rojas, Orla Gray, Dheeraj Khurana, Bart Van Wijmeersch, Nikolaos Grigoriadis, Jihad Inshasi, Jiwon Oh, Eduardo Aguera-Morales, Yara Fragoso, Fraser Moore, Cameron Shaw, Seyed Mohammad Baghbanian, Neil Shuey, Barbara Willekens, Todd A Hardy, Danny Decoo, Angel Perez Sempere, Deborah Field, Ray Wynford-Thomas, Nick G Cunniffe, Izanne Roos, Charles B Malpas, Alasdair J Coles, Tomas Kalincik, J William L Brown
Mult Scler. 2023 Feb 27:13524585231151951. doi: 10.1177/13524585231151951. Online ahead of print.
Comparative effectiveness in multiple sclerosis: A methodological comparison
Izanne Roos, Ibrahima Diouf, Sifat Sharmin, Dana Horakova, Eva Kubala Havrdova, Francesco Patti, Vahid Shaygannejad, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Marc Girard, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Patrizia Sola, Diana Ferraro, Pierre Grammond, Recai Turkoglu, Katherine Buzzard, Olga Skibina, Bassem Yamou, Ayse Altintas, Oliver Gerlach, Vincent van Pesch, Yolanda Blanco, Davide Maimone, Jeannette Lechner-Scott, Roberto Bergamaschi, Rana Karabudak, Chris McGuigan, Elisabetta Cartechini, Michael Barnett, Stella Hughes, Maria José Sa, Claudio Solaro, Cristina Ramo-Tello, Suzanne Hodgkinson, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Franco Granella, Koen de Gans, Pamela McCombe, Radek Ampapa, Bart Van Wijmeersch, Anneke van der Walt, Helmut Butzkueven, Julie Prevost, Jose Luis Sanchez-Menoyo, Guy Laureys, Riadh Gouider, Tamara Castillo-Triviño, Orla Gray, Eduardo Aguera-Morales, Abdullah Al-Asmi, Cameron Shaw, Norma Deri, Talal Al-Harbi, Yara Fragoso, Tunde Csepany, Angel Perez Sempere, Irene Trevino-Frenk, Jan Schepel, Fraser Moore, Charles Malpas, Tomas Kalincik
Mult Scler. 2023 Mar;29(3):326-332. doi: 10.1177/13524585231151394. Epub 2023 Feb 19.
Variability of the response to immunotherapy among subgroups of patients with multiple sclerosis
Ibrahima Diouf, Charles B Malpas, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Francesco Patti, Vahid Shaygannejad, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Marc Girard, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Sherif Hamdy, Patrizia Sola, Diana Ferraro, Pierre Grammond, Recai Turkoglu, Katherine Buzzard, Olga Skibina, Bassem Yamout, Ayse Altintas, Oliver Gerlach, Vincent van Pesch, Yolanda Blanco, Davide Maimone, Jeannette Lechner-Scott, Roberto Bergamaschi, Rana Karabudak, Gerardo Iuliano, Chris McGuigan, Elisabetta Cartechini, Michael Barnett, Stella Hughes, Maria José Sa, Claudio Solaro, Ludwig Kappos, Cristina Ramo-Tello, Edgardo Cristiano, Suzanne Hodgkinson, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Mark Slee, Ernest Butler, Franco Granella, Koen de Gans, Pamela McCombe, Radek Ampapa, Bart Van Wijmeersch, Anneke van der Walt, Helmut Butzkueven, Julie Prevost, L G F Sinnige, Jose Luis Sanchez-Menoyo, Steve Vucic, Guy Laureys, Liesbeth Van Hijfte, Dheeraj Khurana, Richard Macdonell, Riadh Gouider, Tamara Castillo-Triviño, Orla Gray, Eduardo Aguera-Morales, Abdullah Al-Asmi, Cameron Shaw, Norma Deri, Talal Al-Harbi, Yara Fragoso, Tunde Csepany, Angel Perez Sempere, Irene Trevino-Frenk, Jan Schepel, Fraser Moore, Tomas Kalincik
Eur J Neurol. 2023 Apr;30(4):1014-1024. doi: 10.1111/ene.15706. Epub 2023 Feb 16.
Comparing switch to ocrelizumab, cladribine or natalizumab after fingolimod treatment cessation in multiple sclerosis
Chao Zhu, Zhen Zhou, Izanne Roos, Daniel Merlo, Tomas Kalincik, Serkan Ozakbas, Olga Skibina, Jens Kuhle, Suzanne Hodgkinson, Cavit Boz, Raed Alroughani, Jeannette Lechner-Scott, Michael Barnett, Guillermo Izquierdo, Alexandre Prat, Dana Horakova, Eva Kubala Havrdova, Richard Macdonell, Francesco Patti, Samia Joseph Khoury, Mark Slee, Rana Karabudak, Marco Onofrj, Vincent Van Pesch, Julie Prevost, Mastura Monif, Vilija Jokubaitis, Anneke van der Walt, Helmut Butzkueven, MSBase Study Group
J Neurol Neurosurg Psychiatry. 2022 Dec;93(12):1330-1337. doi: 10.1136/jnnp-2022-330104. Epub 2022 Oct 19.
Early predictors of disability in paediatric multiple sclerosis: evidence from a multi-national registry
Sifat Sharmin, Charles B Malpas, Izanne Roos, Ibrahima Diouf, Raed Alroughani, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Dana Horakova, Eva K Havrdova, Francesco Patti, Murat Terzi, Cavit Boz, Bassem Yamout, Samia J Khoury, Marco Onofrj, Alessandra Lugaresi, Ayse Altintas, Alexandre Prat, Marc Girard, Pierre Duquette, Maria José Sá, Daniele La Spitaleri, Youssef Sidhom, Riadh Gouider, Saloua Mrabet, Aysun Soysal, Recai Turkoglu, Maria Pia Amato, Yara D Fragoso, Tomas Kalincik
J Neurol Neurosurg Psychiatry. 2022 Sep 30:jnnp-2022-329713. doi: 10.1136/jnnp-2022-329713. Online ahead of print.
Disease Reactivation After Cessation of Disease-Modifying Therapy in Patients With Relapsing-Remitting Multiple Sclerosis
Izanne Roos, Charles Malpas, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Kubala Havrdova, Marc Debouverie, Francesco Patti, Jerome De Seze, Guillermo Izquierdo, Sara Eichau, Gilles Edan, Alexandre Prat, Marc Girard, Serkan Ozakbas, Pierre Grammond, Helene Zephir, Jonathan Ciron, Elisabeth Maillart, Thibault Moreau, Maria Pia Amato, Pierre Labauge, Raed Alroughani, Katherine Buzzard, Olga Skibina, Murat Terzi, David Axel Laplaud, Eric Berger, Francois Grand'Maison, Christine Lebrun-Frenay, Elisabetta Cartechini, Cavit Boz, Jeannette Lechner-Scott, Pierre Clavelou, Bruno Stankoff, Julie Prevost, Ludwig Kappos, Jean Pelletier, Vahid Shaygannejad, Bassem I Yamout, Samia J Khoury, Oliver Gerlach, Daniele L A Spitaleri, Vincent Van Pesch, Olivier Gout, Recai Turkoglu, Olivier Heinzlef, Eric Thouvenot, Pamela Ann McCombe, Aysun Soysal, Bertrand Bourre, Mark Slee, Tamara Castillo-Trivino, Serge Bakchine, Radek Ampapa, Ernest Gerard Butler, Abir Wahab, Richard A Macdonell, Eduardo Aguera-Morales, Philippe Cabre, Nasr Haifa Ben, Anneke Van der Walt, Guy Laureys, Liesbeth Van Hijfte, Cristina M Ramo-Tello, Nicolas Maubeuge, Suzanne Hodgkinson, José Luis Sánchez-Menoyo, Michael H Barnett, Celine Labeyrie, Steve Vucic, Youssef Sidhom, Riadh Gouider, Tunde Csepany, Javier Sotoca, Koen de Gans, Abdullah Al-Asmi, Yara Dadalti Fragoso, Sandra Vukusic, Helmut Butzkueven, Tomas Kalincik, MSBase and OFSEP
Neurology. 2022 Oct 25;99(17):e1926-e1944. doi: 10.1212/WNL.0000000000201029. Epub 2022 Aug 17.
Impact of telehealth on health care in a multiple sclerosis outpatient clinic during the COVID-19 pandemic
Vivien Li, Izanne Roos, Mastura Monif, Charles Malpas, Stefanie Roberts, Mark Marriott, Katherine Buzzard, Ai-Lan Nguyen, Nabil Seery, Lisa Taylor, Tomas Kalincik, Trevor Kilpatrick
Mult Scler Relat Disord. 2022 Jul;63:103913. doi: 10.1016/j.msard.2022.103913. Epub 2022 May 27.
Multiple Sclerosis Relapses Following Cessation of Fingolimod
Charles B Malpas, Izanne Roos, Sifat Sharmin, Katherine Buzzard, Olga Skibina, Helmut Butzkueven, Ludwig Kappos, Francesco Patti, Raed Alroughani, Dana Horakova, Eva Kubala Havrdova, Guillermo Izquierdo, Sara Eichau, Suzanne Hodgkinson, Pierre Grammond, Jeannette Lechner-Scott, Tomas Kalincik, MSBase Study Group
Clin Drug Investig. 2022 Apr;42(4):355-364. doi: 10.1007/s40261-022-01129-7. Epub 2022 Mar 18.
The dynamics of relapses during treatment switch in relapsing-remitting multiple sclerosis
Federico Frascoli, Izanne Roos, Charles B Malpas, Tomas Kalincik
J Theor Biol. 2022 May 21;541:111091. doi: 10.1016/j.jtbi.2022.111091. Epub 2022 Mar 11.
Effects of High- and Low-Efficacy Therapy in Secondary Progressive Multiple Sclerosis
Izanne Roos, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Havrdova, Guillermo Izquierdo, Sara Eichau Madueño, Francesco Patti, Gilles Edan, Marc Debouverie, Jean Pelletier, Serkan Ozakbas, Maria Pia Amato, Pierre Clavelou, Pierre Grammond, Cavit Boz, Katherine Buzzard, Olga Skibina, Jonathan Ciron, Oliver Gerlach, Francois Grand'Maison, Jeannette Lechner-Scott, Charles Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik, MSBase and OFSEP Study Groups
Neurology. 2021 Aug 31;97(9):e869-e880. doi: 10.1212/WNL.0000000000012354. Epub 2021 Jun 30.
Predicting Infection Risk in Multiple Sclerosis Patients Treated with Ocrelizumab: A Retrospective Cohort Study
Nabil Seery, Sifat Sharmin, Vivien Li, Ai-Lan Nguyen, Claire Meaton, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Mark P Marriott, Katherine A Buzzard, Izanne Roos, Chris Dwyer, Josephine Baker, Lisa Taylor, Kymble Spriggs, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
CNS Drugs. 2021 Aug;35(8):907-918. doi: 10.1007/s40263-021-00810-3. Epub 2021 Apr 13.
Determinants of therapeutic lag in multiple sclerosis
Izanne Roos, Emmanuelle Leray, Federico Frascoli, Romain Casey, J William L Brown, Dana Horakova, Eva Kubala Havrdova, Marc Debouverie, Maria Trojano, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Gilles Edan, Alexandre Prat, Marc Girard, Pierre Duquette, Marco Onofrj, Alessandra Lugaresi, Pierre Grammond, Jonathan Ciron, Aurélie Ruet, Serkan Ozakbas, Jérôme De Seze, Céline Louapre, Hélène Zephir, Maria José Sá, Patrizia Sola, Diana Ferraro, Pierre Labauge, Gilles Defer, Roberto Bergamaschi, Christine Lebrun-Frenay, Cavit Boz, Elisabetta Cartechini, Thibault Moreau, David Laplaud, Jeannette Lechner-Scott, Francois Grand'Maison, Oliver Gerlach, Murat Terzi, Franco Granella, Raed Alroughani, Gerardo Iuliano, Vincent Van Pesch, Bart Van Wijmeersch, Daniele LA Spitaleri, Aysun Soysal, Eric Berger, Julie Prevost, Eduardo Aguera-Morales, Pamela McCombe, Tamara Castillo Triviño, Pierre Clavelou, Jean Pelletier, Recai Turkoglu, Bruno Stankoff, Olivier Gout, Eric Thouvenot, Olivier Heinzlef, Youssef Sidhom, Riadh Gouider, Tunde Csepany, Bertrand Bourre, Abdullatif Al Khedr, Olivier Casez, Philippe Cabre, Alexis Montcuquet, Abir Wahab, Jean-Philippe Camdessanche, Aude Maurousset, Ivania Patry, Karolina Hankiewicz, Corinne Pottier, Nicolas Maubeuge, Céline Labeyrie, Chantal Nifle, Alasdair Coles, Charles B Malpas, Sandra Vukusic, Helmut Butzkueven, Tomas Kalincik
Mult Scler. 2021 Oct;27(12):1838-1851. doi: 10.1177/1352458520981300. Epub 2021 Jan 11.
Evaluating the perspective of patients with MS and related conditions on their DMT in relation to the COVID-19 pandemic in one MS centre in Australia
Nabil Seery, Vivien Li, Ai-Lan Nguyen, Izanne Roos, Katherine A Buzzard, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Chris Dwyer, Hasini Fernandoa Lisa Taylor, Josephine Baker, Mark P Marriott, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
Mult Scler Relat Disord. 2020 Nov;46:102516. doi: 10.1016/j.msard.2020.102516. Epub 2020 Sep 16.
Delay from treatment start to full effect of immunotherapies for multiple sclerosis
Izanne Roos, Emmanuelle Leray, Federico Frascoli, Romain Casey, J William L Brown, Dana Horakova, Eva K Havrdova, Maria Trojano, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Grammond, Patrizia Sola, Diana Ferraro, Serkan Ozakbas, Roberto Bergamaschi, Maria José Sá, Elisabetta Cartechini, Cavit Boz, Franco Granella, Raymond Hupperts, Murat Terzi, Jeannette Lechner-Scott, Daniele Spitaleri, Vincent Van Pesch, Aysun Soysal, Javier Olascoaga, Julie Prevost, Eduardo Aguera-Morales, Mark Slee, Tunde Csepany, Recai Turkoglu, Youssef Sidhom, Riadh Gouider, Bart Van Wijmeersch, Pamela McCombe, Richard Macdonell, Alasdair Coles, Charles B Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik, MSBase, OFSEP investigators
Brain. 2020 Sep 1;143(9):2742-2756. doi: 10.1093/brain/awaa231.
Early clinical markers of aggressive multiple sclerosis
Charles B Malpas, Ali Manouchehrinia, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Maria Trojano, Guillermo Izquierdo, Sara Eichau, Roberto Bergamaschi, Patrizia Sola, Diana Ferraro, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Francois Grand'Maison, Serkan Ozakbas, Vincent Van Pesch, Franco Granella, Raymond Hupperts, Eugenio Pucci, Cavit Boz, Youssef Sidhom, Riadh Gouider, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Freek Verheul, Rana Karabudak, Recai Turkoglu, Cristina Ramo-Tello, Murat Terzi, Edgardo Cristiano, Mark Slee, Pamela McCombe, Richard Macdonell, Yara Fragoso, Javier Olascoaga, Ayse Altintas, Tomas Olsson, Helmut Butzkueven, Jan Hillert, Tomas Kalincik
Brain. 2020 May 1;143(5):1400-1413. doi: 10.1093/brain/awaa081.
Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures
Albert D Wang, Michelle Leong, Benjamin Johnstone, Genevieve Rayner, Tomas Kalincik, Izanne Roos, Patrick Kwan, Terence J O'Brien, Dennis Velakoulis, Charles B Malpas
Epilepsy Res. 2019 Dec;158:106234. doi: 10.1016/j.eplepsyres.2019.106234. Epub 2019 Nov 1.
Personality profiles differ between patients with epileptic seizures and patients with psychogenic non-epileptic seizures
Michelle Leong, Albert D Wang, David Trainor, Ben Johnstone, Genevieve Rayner, Tomas Kalincik, Izanne Roos, Patrick Kwan, Terence J O'Brien, Dennis Velakoulis, Charles B Malpas
Seizure. 2019 Dec;73:1-8. doi: 10.1016/j.seizure.2019.10.011. Epub 2019 Oct 17.
Posttubercular syringomyelia in HIV-infected patients: A report of 10 cases and literature review
Suzaan Marais, Izanne Roos, Ayesha Mitha, Vinod Patel, Ahmed I Bhigjee
J Neurol Sci. 2018 Dec 15;395:54-61. doi: 10.1016/j.jns.2018.09.034. Epub 2018 Sep 28.
The neuromyelitis optica presentation and the aquaporin-4 antibody in HIV-seropositive and seronegative patients in KwaZulu-Natal, South Africa
Ahmed I Bhigjee, Anandan A Moodley, Izanne Roos, Cait-Lynn Wells, Pratistadevi Ramdial, Monika Esser
South Afr J HIV Med. 2017 Jan 31;18(1):684. doi: 10.4102/sajhivmed.v18i1.684. eCollection 2017.
Spinal Tuberculosis: Clinicoradiological Findings in 274 Patients
Suzaan Marais, Izanne Roos, Ayesha Mitha, Sepelong J Mabusha, Vinod Patel, Ahmed I Bhigjee
Clin Infect Dis. 2018 Jun 18;67(1):89-98. doi: 10.1093/cid/ciy020.
Cyrus Daruwalla, Vahid Shaygannejad, Serkan Ozakbas, Eva Kubala Havrdova, Dana Horakova, Raed Alroughani, Cavit Boz, Francesco Patti, Marco Onofrj, Alessandra Lugaresi, Sara Eichau, Marc Girard, Alexandre Prat, Pierre Duquette, Bassem Yamout, Samia J Khoury, Seyed Aidin Sajedi, Recai Turkoglu, Ayse Altintas, Olga Skibina, Katherine Buzzard, Pierre Grammond, Rana Karabudak, Anneke van der Walt, Helmut Butzkueven, Davide Maimone, Jeannette Lechner-Scott, Aysun Soysal, Nevin John, Julie Prevost, Daniele Spitaleri, Cristina Ramo-Tello, Oliver Gerlach, Gerardo Iuliano, Matteo Foschi, Radek Ampapa, Vincent van Pesch, Michael Barnett, Nevin Shalaby, Marie D'hooghe, Jens Kuhle, Maria Jose Sa, Marzena Fabis-Pedrini, Allan Kermode, Saloua Mrabet, Riadh Gouider, Suzanne Hodgkinson, Guy Laureys, Liesbeth Van Hijfte, Richard Macdonell, Celia Oreja-Guevara, Edgardo Cristiano, Pamela McCombe, Jose Luis Sanchez-Menoyo, Bhim Singhal, Yolanda Blanco, Stella Hughes, Justin Garber, Claudio Solaro, Chris McGuigan, Bruce Taylor, Koen de Gans, Mario Habek, Abdullah Al-Asmi, Simu Mihaela, Tamara Castillo Triviño, Talal Al-Harbi, Juan Ignacio Rojas, Orla Gray, Dheeraj Khurana, Bart Van Wijmeersch, Nikolaos Grigoriadis, Jihad Inshasi, Jiwon Oh, Eduardo Aguera-Morales, Yara Fragoso, Fraser Moore, Cameron Shaw, Seyed Mohammad Baghbanian, Neil Shuey, Barbara Willekens, Todd A Hardy, Danny Decoo, Angel Perez Sempere, Deborah Field, Ray Wynford-Thomas, Nick G Cunniffe, Izanne Roos, Charles B Malpas, Alasdair J Coles, Tomas Kalincik, J William L Brown
Mult Scler. 2023 Feb 27:13524585231151951. doi: 10.1177/13524585231151951. Online ahead of print.
Comparative effectiveness in multiple sclerosis: A methodological comparison
Izanne Roos, Ibrahima Diouf, Sifat Sharmin, Dana Horakova, Eva Kubala Havrdova, Francesco Patti, Vahid Shaygannejad, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Marc Girard, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Patrizia Sola, Diana Ferraro, Pierre Grammond, Recai Turkoglu, Katherine Buzzard, Olga Skibina, Bassem Yamou, Ayse Altintas, Oliver Gerlach, Vincent van Pesch, Yolanda Blanco, Davide Maimone, Jeannette Lechner-Scott, Roberto Bergamaschi, Rana Karabudak, Chris McGuigan, Elisabetta Cartechini, Michael Barnett, Stella Hughes, Maria José Sa, Claudio Solaro, Cristina Ramo-Tello, Suzanne Hodgkinson, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Franco Granella, Koen de Gans, Pamela McCombe, Radek Ampapa, Bart Van Wijmeersch, Anneke van der Walt, Helmut Butzkueven, Julie Prevost, Jose Luis Sanchez-Menoyo, Guy Laureys, Riadh Gouider, Tamara Castillo-Triviño, Orla Gray, Eduardo Aguera-Morales, Abdullah Al-Asmi, Cameron Shaw, Norma Deri, Talal Al-Harbi, Yara Fragoso, Tunde Csepany, Angel Perez Sempere, Irene Trevino-Frenk, Jan Schepel, Fraser Moore, Charles Malpas, Tomas Kalincik
Mult Scler. 2023 Mar;29(3):326-332. doi: 10.1177/13524585231151394. Epub 2023 Feb 19.
Variability of the response to immunotherapy among subgroups of patients with multiple sclerosis
Ibrahima Diouf, Charles B Malpas, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Francesco Patti, Vahid Shaygannejad, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Marc Girard, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Sherif Hamdy, Patrizia Sola, Diana Ferraro, Pierre Grammond, Recai Turkoglu, Katherine Buzzard, Olga Skibina, Bassem Yamout, Ayse Altintas, Oliver Gerlach, Vincent van Pesch, Yolanda Blanco, Davide Maimone, Jeannette Lechner-Scott, Roberto Bergamaschi, Rana Karabudak, Gerardo Iuliano, Chris McGuigan, Elisabetta Cartechini, Michael Barnett, Stella Hughes, Maria José Sa, Claudio Solaro, Ludwig Kappos, Cristina Ramo-Tello, Edgardo Cristiano, Suzanne Hodgkinson, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Mark Slee, Ernest Butler, Franco Granella, Koen de Gans, Pamela McCombe, Radek Ampapa, Bart Van Wijmeersch, Anneke van der Walt, Helmut Butzkueven, Julie Prevost, L G F Sinnige, Jose Luis Sanchez-Menoyo, Steve Vucic, Guy Laureys, Liesbeth Van Hijfte, Dheeraj Khurana, Richard Macdonell, Riadh Gouider, Tamara Castillo-Triviño, Orla Gray, Eduardo Aguera-Morales, Abdullah Al-Asmi, Cameron Shaw, Norma Deri, Talal Al-Harbi, Yara Fragoso, Tunde Csepany, Angel Perez Sempere, Irene Trevino-Frenk, Jan Schepel, Fraser Moore, Tomas Kalincik
Eur J Neurol. 2023 Apr;30(4):1014-1024. doi: 10.1111/ene.15706. Epub 2023 Feb 16.
Comparing switch to ocrelizumab, cladribine or natalizumab after fingolimod treatment cessation in multiple sclerosis
Chao Zhu, Zhen Zhou, Izanne Roos, Daniel Merlo, Tomas Kalincik, Serkan Ozakbas, Olga Skibina, Jens Kuhle, Suzanne Hodgkinson, Cavit Boz, Raed Alroughani, Jeannette Lechner-Scott, Michael Barnett, Guillermo Izquierdo, Alexandre Prat, Dana Horakova, Eva Kubala Havrdova, Richard Macdonell, Francesco Patti, Samia Joseph Khoury, Mark Slee, Rana Karabudak, Marco Onofrj, Vincent Van Pesch, Julie Prevost, Mastura Monif, Vilija Jokubaitis, Anneke van der Walt, Helmut Butzkueven, MSBase Study Group
J Neurol Neurosurg Psychiatry. 2022 Dec;93(12):1330-1337. doi: 10.1136/jnnp-2022-330104. Epub 2022 Oct 19.
Early predictors of disability in paediatric multiple sclerosis: evidence from a multi-national registry
Sifat Sharmin, Charles B Malpas, Izanne Roos, Ibrahima Diouf, Raed Alroughani, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Dana Horakova, Eva K Havrdova, Francesco Patti, Murat Terzi, Cavit Boz, Bassem Yamout, Samia J Khoury, Marco Onofrj, Alessandra Lugaresi, Ayse Altintas, Alexandre Prat, Marc Girard, Pierre Duquette, Maria José Sá, Daniele La Spitaleri, Youssef Sidhom, Riadh Gouider, Saloua Mrabet, Aysun Soysal, Recai Turkoglu, Maria Pia Amato, Yara D Fragoso, Tomas Kalincik
J Neurol Neurosurg Psychiatry. 2022 Sep 30:jnnp-2022-329713. doi: 10.1136/jnnp-2022-329713. Online ahead of print.
Disease Reactivation After Cessation of Disease-Modifying Therapy in Patients With Relapsing-Remitting Multiple Sclerosis
Izanne Roos, Charles Malpas, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Kubala Havrdova, Marc Debouverie, Francesco Patti, Jerome De Seze, Guillermo Izquierdo, Sara Eichau, Gilles Edan, Alexandre Prat, Marc Girard, Serkan Ozakbas, Pierre Grammond, Helene Zephir, Jonathan Ciron, Elisabeth Maillart, Thibault Moreau, Maria Pia Amato, Pierre Labauge, Raed Alroughani, Katherine Buzzard, Olga Skibina, Murat Terzi, David Axel Laplaud, Eric Berger, Francois Grand'Maison, Christine Lebrun-Frenay, Elisabetta Cartechini, Cavit Boz, Jeannette Lechner-Scott, Pierre Clavelou, Bruno Stankoff, Julie Prevost, Ludwig Kappos, Jean Pelletier, Vahid Shaygannejad, Bassem I Yamout, Samia J Khoury, Oliver Gerlach, Daniele L A Spitaleri, Vincent Van Pesch, Olivier Gout, Recai Turkoglu, Olivier Heinzlef, Eric Thouvenot, Pamela Ann McCombe, Aysun Soysal, Bertrand Bourre, Mark Slee, Tamara Castillo-Trivino, Serge Bakchine, Radek Ampapa, Ernest Gerard Butler, Abir Wahab, Richard A Macdonell, Eduardo Aguera-Morales, Philippe Cabre, Nasr Haifa Ben, Anneke Van der Walt, Guy Laureys, Liesbeth Van Hijfte, Cristina M Ramo-Tello, Nicolas Maubeuge, Suzanne Hodgkinson, José Luis Sánchez-Menoyo, Michael H Barnett, Celine Labeyrie, Steve Vucic, Youssef Sidhom, Riadh Gouider, Tunde Csepany, Javier Sotoca, Koen de Gans, Abdullah Al-Asmi, Yara Dadalti Fragoso, Sandra Vukusic, Helmut Butzkueven, Tomas Kalincik, MSBase and OFSEP
Neurology. 2022 Oct 25;99(17):e1926-e1944. doi: 10.1212/WNL.0000000000201029. Epub 2022 Aug 17.
Impact of telehealth on health care in a multiple sclerosis outpatient clinic during the COVID-19 pandemic
Vivien Li, Izanne Roos, Mastura Monif, Charles Malpas, Stefanie Roberts, Mark Marriott, Katherine Buzzard, Ai-Lan Nguyen, Nabil Seery, Lisa Taylor, Tomas Kalincik, Trevor Kilpatrick
Mult Scler Relat Disord. 2022 Jul;63:103913. doi: 10.1016/j.msard.2022.103913. Epub 2022 May 27.
Multiple Sclerosis Relapses Following Cessation of Fingolimod
Charles B Malpas, Izanne Roos, Sifat Sharmin, Katherine Buzzard, Olga Skibina, Helmut Butzkueven, Ludwig Kappos, Francesco Patti, Raed Alroughani, Dana Horakova, Eva Kubala Havrdova, Guillermo Izquierdo, Sara Eichau, Suzanne Hodgkinson, Pierre Grammond, Jeannette Lechner-Scott, Tomas Kalincik, MSBase Study Group
Clin Drug Investig. 2022 Apr;42(4):355-364. doi: 10.1007/s40261-022-01129-7. Epub 2022 Mar 18.
The dynamics of relapses during treatment switch in relapsing-remitting multiple sclerosis
Federico Frascoli, Izanne Roos, Charles B Malpas, Tomas Kalincik
J Theor Biol. 2022 May 21;541:111091. doi: 10.1016/j.jtbi.2022.111091. Epub 2022 Mar 11.
Effects of High- and Low-Efficacy Therapy in Secondary Progressive Multiple Sclerosis
Izanne Roos, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Havrdova, Guillermo Izquierdo, Sara Eichau Madueño, Francesco Patti, Gilles Edan, Marc Debouverie, Jean Pelletier, Serkan Ozakbas, Maria Pia Amato, Pierre Clavelou, Pierre Grammond, Cavit Boz, Katherine Buzzard, Olga Skibina, Jonathan Ciron, Oliver Gerlach, Francois Grand'Maison, Jeannette Lechner-Scott, Charles Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik, MSBase and OFSEP Study Groups
Neurology. 2021 Aug 31;97(9):e869-e880. doi: 10.1212/WNL.0000000000012354. Epub 2021 Jun 30.
Predicting Infection Risk in Multiple Sclerosis Patients Treated with Ocrelizumab: A Retrospective Cohort Study
Nabil Seery, Sifat Sharmin, Vivien Li, Ai-Lan Nguyen, Claire Meaton, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Mark P Marriott, Katherine A Buzzard, Izanne Roos, Chris Dwyer, Josephine Baker, Lisa Taylor, Kymble Spriggs, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
CNS Drugs. 2021 Aug;35(8):907-918. doi: 10.1007/s40263-021-00810-3. Epub 2021 Apr 13.
Determinants of therapeutic lag in multiple sclerosis
Izanne Roos, Emmanuelle Leray, Federico Frascoli, Romain Casey, J William L Brown, Dana Horakova, Eva Kubala Havrdova, Marc Debouverie, Maria Trojano, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Gilles Edan, Alexandre Prat, Marc Girard, Pierre Duquette, Marco Onofrj, Alessandra Lugaresi, Pierre Grammond, Jonathan Ciron, Aurélie Ruet, Serkan Ozakbas, Jérôme De Seze, Céline Louapre, Hélène Zephir, Maria José Sá, Patrizia Sola, Diana Ferraro, Pierre Labauge, Gilles Defer, Roberto Bergamaschi, Christine Lebrun-Frenay, Cavit Boz, Elisabetta Cartechini, Thibault Moreau, David Laplaud, Jeannette Lechner-Scott, Francois Grand'Maison, Oliver Gerlach, Murat Terzi, Franco Granella, Raed Alroughani, Gerardo Iuliano, Vincent Van Pesch, Bart Van Wijmeersch, Daniele LA Spitaleri, Aysun Soysal, Eric Berger, Julie Prevost, Eduardo Aguera-Morales, Pamela McCombe, Tamara Castillo Triviño, Pierre Clavelou, Jean Pelletier, Recai Turkoglu, Bruno Stankoff, Olivier Gout, Eric Thouvenot, Olivier Heinzlef, Youssef Sidhom, Riadh Gouider, Tunde Csepany, Bertrand Bourre, Abdullatif Al Khedr, Olivier Casez, Philippe Cabre, Alexis Montcuquet, Abir Wahab, Jean-Philippe Camdessanche, Aude Maurousset, Ivania Patry, Karolina Hankiewicz, Corinne Pottier, Nicolas Maubeuge, Céline Labeyrie, Chantal Nifle, Alasdair Coles, Charles B Malpas, Sandra Vukusic, Helmut Butzkueven, Tomas Kalincik
Mult Scler. 2021 Oct;27(12):1838-1851. doi: 10.1177/1352458520981300. Epub 2021 Jan 11.
Evaluating the perspective of patients with MS and related conditions on their DMT in relation to the COVID-19 pandemic in one MS centre in Australia
Nabil Seery, Vivien Li, Ai-Lan Nguyen, Izanne Roos, Katherine A Buzzard, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Chris Dwyer, Hasini Fernandoa Lisa Taylor, Josephine Baker, Mark P Marriott, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
Mult Scler Relat Disord. 2020 Nov;46:102516. doi: 10.1016/j.msard.2020.102516. Epub 2020 Sep 16.
Delay from treatment start to full effect of immunotherapies for multiple sclerosis
Izanne Roos, Emmanuelle Leray, Federico Frascoli, Romain Casey, J William L Brown, Dana Horakova, Eva K Havrdova, Maria Trojano, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Grammond, Patrizia Sola, Diana Ferraro, Serkan Ozakbas, Roberto Bergamaschi, Maria José Sá, Elisabetta Cartechini, Cavit Boz, Franco Granella, Raymond Hupperts, Murat Terzi, Jeannette Lechner-Scott, Daniele Spitaleri, Vincent Van Pesch, Aysun Soysal, Javier Olascoaga, Julie Prevost, Eduardo Aguera-Morales, Mark Slee, Tunde Csepany, Recai Turkoglu, Youssef Sidhom, Riadh Gouider, Bart Van Wijmeersch, Pamela McCombe, Richard Macdonell, Alasdair Coles, Charles B Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik, MSBase, OFSEP investigators
Brain. 2020 Sep 1;143(9):2742-2756. doi: 10.1093/brain/awaa231.
Early clinical markers of aggressive multiple sclerosis
Charles B Malpas, Ali Manouchehrinia, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Maria Trojano, Guillermo Izquierdo, Sara Eichau, Roberto Bergamaschi, Patrizia Sola, Diana Ferraro, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Francois Grand'Maison, Serkan Ozakbas, Vincent Van Pesch, Franco Granella, Raymond Hupperts, Eugenio Pucci, Cavit Boz, Youssef Sidhom, Riadh Gouider, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Freek Verheul, Rana Karabudak, Recai Turkoglu, Cristina Ramo-Tello, Murat Terzi, Edgardo Cristiano, Mark Slee, Pamela McCombe, Richard Macdonell, Yara Fragoso, Javier Olascoaga, Ayse Altintas, Tomas Olsson, Helmut Butzkueven, Jan Hillert, Tomas Kalincik
Brain. 2020 May 1;143(5):1400-1413. doi: 10.1093/brain/awaa081.
Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures
Albert D Wang, Michelle Leong, Benjamin Johnstone, Genevieve Rayner, Tomas Kalincik, Izanne Roos, Patrick Kwan, Terence J O'Brien, Dennis Velakoulis, Charles B Malpas
Epilepsy Res. 2019 Dec;158:106234. doi: 10.1016/j.eplepsyres.2019.106234. Epub 2019 Nov 1.
Personality profiles differ between patients with epileptic seizures and patients with psychogenic non-epileptic seizures
Michelle Leong, Albert D Wang, David Trainor, Ben Johnstone, Genevieve Rayner, Tomas Kalincik, Izanne Roos, Patrick Kwan, Terence J O'Brien, Dennis Velakoulis, Charles B Malpas
Seizure. 2019 Dec;73:1-8. doi: 10.1016/j.seizure.2019.10.011. Epub 2019 Oct 17.
Posttubercular syringomyelia in HIV-infected patients: A report of 10 cases and literature review
Suzaan Marais, Izanne Roos, Ayesha Mitha, Vinod Patel, Ahmed I Bhigjee
J Neurol Sci. 2018 Dec 15;395:54-61. doi: 10.1016/j.jns.2018.09.034. Epub 2018 Sep 28.
The neuromyelitis optica presentation and the aquaporin-4 antibody in HIV-seropositive and seronegative patients in KwaZulu-Natal, South Africa
Ahmed I Bhigjee, Anandan A Moodley, Izanne Roos, Cait-Lynn Wells, Pratistadevi Ramdial, Monika Esser
South Afr J HIV Med. 2017 Jan 31;18(1):684. doi: 10.4102/sajhivmed.v18i1.684. eCollection 2017.
Spinal Tuberculosis: Clinicoradiological Findings in 274 Patients
Suzaan Marais, Izanne Roos, Ayesha Mitha, Sepelong J Mabusha, Vinod Patel, Ahmed I Bhigjee
Clin Infect Dis. 2018 Jun 18;67(1):89-98. doi: 10.1093/cid/ciy020.