Introducing
Dr Sifat Sharmin
Hello, I’m Sifat, a Biostatistician and Senior Research Fellow in the Clinical Outcomes Research (CORe) Unit.
Dr Sifat Sharmin
Biostatistician & Senior Research Fellow (Multiple Sclerosis)
PhD (Biostatistics), MSc & BSc (Honours) in Applied Statistics
a little bit about me
Trained as a statistician, I am passionate about integrating statistical innovation with clinical insights to inform evidence-based clinical decisions. Much of my recent work focuses on leveraging observational data to explore prognosis and treatment outcomes in paediatric multiple sclerosis.
My research has been supported by the MSBase Foundation Fellowship and is currently funded by a MS Australia Postdoctoral Fellowship. My current research interests include prognostics, heterogeneous treatment effects, personalized treatment approaches, joint modelling, Bayesian statistical methods, and causal inference.
Publications
Preserving Neurological Function in People at High and Low Risk of Aggressive Multiple Sclerosis: An Observational Cohort Study
Izanne Roos, Sifat Sharmin, Serkan Ozakbas, Raed Alroughani, Sara Eichau, Francois Grand'Maison, Cavit Boz, Jeannette Lechner-Scott, Katherine Buzzard, Alexandre Prat, Samia J Khoury, Pierre Grammond, Anneke van der Walt, Yolanda Blanco, Matteo Foschi, Aysun Soysal, Michael Barnett, Julie Prevost, Murat Terzi, Oliver Gerlach, Richard Macdonell, Maria Jose Sa, Daniele Spitaleri, Guy Laureys, Vincent van Pesch, Nevin John, Elisabetta Cartechini, Riadh Gouider, Davide Maimone, Cristina Ramo-Tello, Suzanne Hodgkinson, Mark Slee, Pamela McCombe, Justin Garber, Jose Luis Sanchez-Menoyo, Abdullah Al-Asmi, Allan G Kermode, Emmanuelle Lapointe, Vahid Shaygannejad, Bart Van Wijmeersch, Barbara Willekens, Tamara Castillo-Triviño, Bruce Taylor, Guillaume Mathey, Emmanuelle Le Page, Jerome De Seze, Aurelie Ruet, Pierre Clavelou, Eric Berger, Helene Zephir, Arnaud Kwiatkowski, Jean Pelletier, Thibault Moreau, Pierre Labauge, Jonathan Ciron, Christine Lebrun-Frenay, Caroline Papeix, Gilles Defer, David Axel Laplaud, Eric Thouvenot, Bruno Stankoff, Elisabeth Maillart, Abdullatif Al-Khedr, Bertrand Bourre, Olivier Casez, Amélie Dos Santos, Jean-Philippe Camdessanche, Karolina Hankiewicz, Abir Wahab, Philippe Cabre, Olivier Heinzlef, Corinne Pottier, Solène Moulin, Laurent Magy, Céline Labeyrie, Inès Doghri, Sandra Vukusic, Tomas Kalincik, MSBase and OFSEP Study Groups
CNS Drugs. 2026 Jul;40(7):1011-1025. doi: 10.1007/s40263-026-01287-8. Epub 2026 Apr 4.
Treatment De-escalation in Relapsing-Remitting Multiple Sclerosis: An Observational Study
Jannis Müller, Sifat Sharmin, Johannes Lorscheider, Dana Horakova, Eva Kubala Havrdova, Sara Eichau, Francesco Patti, Pierre Grammond, Katherine Buzzard, Olga Skibina, Alexandre Prat, Marc Girard, Francois Grand'Maison, Raed Alroughani, Jeannette Lechner-Scott, Daniele Spitaleri, Michael Barnett, Elisabetta Cartechini, Maria Jose Sa, Oliver Gerlach, Anneke van der Walt, Helmut Butzkueven, Julie Prevost, Tamara Castillo-Triviño, Bassem Yamout, Samia J Khoury, Özgür Yaldizli, Tobias Derfuss, Cristina Granziera, Jens Kuhle, Ludwig Kappos, Izanne Roos, Tomas Kalincik, MSBase Study Group
CNS Drugs. 2025 Apr;39(4):403-416. doi: 10.1007/s40263-025-01164-w. Epub 2025 Feb 14.
Escalating to medium- versus high-efficacy disease modifying therapy after low-efficacy treatment in relapsing remitting multiple sclerosis
Jannis Müller, Izanne Roos, Tomas Kalincik, Johannes Lorscheider, Edoardo Galli, Pascal Benkert, Sabine Schädelin, Sifat Sharmin, Maximilian Einsiedler, Peter Hänni, Jürg Schmid, Jens Kuhle, Tobias Derfuss, Cristina Granziera, Tjalf Ziemssen, Timo Siepmann, Özgür Yaldizli
Brain Behav. 2024 May;14(5):e3498. doi: 10.1002/brb3.3498.
Severity of COVID19 infection among patients with multiple sclerosis treated with interferon-β
Steve Simpson-Yap, Ashkan Pirmani, Edward De Brouwer, Liesbet M Peeters, Lotte Geys, Tina Parciak, Anne Helme, Jan Hillert, Yves Moreau, Gilles Edan, Tim Spelman, Sifat Sharmin, Robert McBurney, Hollie Schmidt, Arnfin Bergmann, Stefan Braune, Alexander Stahmann, Rodden Middleton, Amber Salter, Bruce Bebo, Anneke van der Walt, Helmut Butzkueven, Serkan Ozakbas, Rana Karabudak, Cavit Boz, Raed Alroughani, Juan I Rojas, Ingrid van der Mei, Guilherme Sciascia do Olival, Melinda Magyari, Ricardo Alonso, Richard Nicholas, Anibal Chertcoff, Ana Zabalza, Georgina Arrambide, Nupur Nag, Annabel Descamps, Lars Costers, Ruth Dobson, Aleisha Miller, Paulo Rodrigues, Vesna Prčkovska, Giancarlo Comi, Tomas Kalincik
Mult Scler Relat Disord. 2022 Oct;66:104072. doi: 10.1016/j.msard.2022.104072. Epub 2022 Jul 25.
Multiple Sclerosis Relapses Following Cessation of Fingolimod
Charles B Malpas, Izanne Roos, Sifat Sharmin, Katherine Buzzard, Olga Skibina, Helmut Butzkueven, Ludwig Kappos, Francesco Patti, Raed Alroughani, Dana Horakova, Eva Kubala Havrdova, Guillermo Izquierdo, Sara Eichau, Suzanne Hodgkinson, Pierre Grammond, Jeannette Lechner-Scott, Tomas Kalincik, MSBase Study Group
Clin Drug Investig. 2022 Apr;42(4):355-364. doi: 10.1007/s40261-022-01129-7. Epub 2022 Mar 18.
A stochastic model for early identification of infectious disease epidemics with application to measles cases in Bangladesh
Sifat Sharmin, Md Israt Rayhan
Asia Pac J Public Health. 2015 Mar;27(2):NP816-23. doi: 10.1177/1010539512461668. Epub 2012 Nov 18.
Modelling of infectious diseases for providing signal of epidemics: a measles case study in Bangladesh
Sifat Sharmin, Israt Rayhan
J Health Popul Nutr. 2011 Dec;29(6):567-73. doi: 10.3329/jhpn.v29i6.9893.
Izanne Roos, Sifat Sharmin, Serkan Ozakbas, Raed Alroughani, Sara Eichau, Francois Grand'Maison, Cavit Boz, Jeannette Lechner-Scott, Katherine Buzzard, Alexandre Prat, Samia J Khoury, Pierre Grammond, Anneke van der Walt, Yolanda Blanco, Matteo Foschi, Aysun Soysal, Michael Barnett, Julie Prevost, Murat Terzi, Oliver Gerlach, Richard Macdonell, Maria Jose Sa, Daniele Spitaleri, Guy Laureys, Vincent van Pesch, Nevin John, Elisabetta Cartechini, Riadh Gouider, Davide Maimone, Cristina Ramo-Tello, Suzanne Hodgkinson, Mark Slee, Pamela McCombe, Justin Garber, Jose Luis Sanchez-Menoyo, Abdullah Al-Asmi, Allan G Kermode, Emmanuelle Lapointe, Vahid Shaygannejad, Bart Van Wijmeersch, Barbara Willekens, Tamara Castillo-Triviño, Bruce Taylor, Guillaume Mathey, Emmanuelle Le Page, Jerome De Seze, Aurelie Ruet, Pierre Clavelou, Eric Berger, Helene Zephir, Arnaud Kwiatkowski, Jean Pelletier, Thibault Moreau, Pierre Labauge, Jonathan Ciron, Christine Lebrun-Frenay, Caroline Papeix, Gilles Defer, David Axel Laplaud, Eric Thouvenot, Bruno Stankoff, Elisabeth Maillart, Abdullatif Al-Khedr, Bertrand Bourre, Olivier Casez, Amélie Dos Santos, Jean-Philippe Camdessanche, Karolina Hankiewicz, Abir Wahab, Philippe Cabre, Olivier Heinzlef, Corinne Pottier, Solène Moulin, Laurent Magy, Céline Labeyrie, Inès Doghri, Sandra Vukusic, Tomas Kalincik, MSBase and OFSEP Study Groups
CNS Drugs. 2026 Jul;40(7):1011-1025. doi: 10.1007/s40263-026-01287-8. Epub 2026 Apr 4.
Treatment De-escalation in Relapsing-Remitting Multiple Sclerosis: An Observational Study
Jannis Müller, Sifat Sharmin, Johannes Lorscheider, Dana Horakova, Eva Kubala Havrdova, Sara Eichau, Francesco Patti, Pierre Grammond, Katherine Buzzard, Olga Skibina, Alexandre Prat, Marc Girard, Francois Grand'Maison, Raed Alroughani, Jeannette Lechner-Scott, Daniele Spitaleri, Michael Barnett, Elisabetta Cartechini, Maria Jose Sa, Oliver Gerlach, Anneke van der Walt, Helmut Butzkueven, Julie Prevost, Tamara Castillo-Triviño, Bassem Yamout, Samia J Khoury, Özgür Yaldizli, Tobias Derfuss, Cristina Granziera, Jens Kuhle, Ludwig Kappos, Izanne Roos, Tomas Kalincik, MSBase Study Group
CNS Drugs. 2025 Apr;39(4):403-416. doi: 10.1007/s40263-025-01164-w. Epub 2025 Feb 14.
Escalating to medium- versus high-efficacy disease modifying therapy after low-efficacy treatment in relapsing remitting multiple sclerosis
Jannis Müller, Izanne Roos, Tomas Kalincik, Johannes Lorscheider, Edoardo Galli, Pascal Benkert, Sabine Schädelin, Sifat Sharmin, Maximilian Einsiedler, Peter Hänni, Jürg Schmid, Jens Kuhle, Tobias Derfuss, Cristina Granziera, Tjalf Ziemssen, Timo Siepmann, Özgür Yaldizli
Brain Behav. 2024 May;14(5):e3498. doi: 10.1002/brb3.3498.
Severity of COVID19 infection among patients with multiple sclerosis treated with interferon-β
Steve Simpson-Yap, Ashkan Pirmani, Edward De Brouwer, Liesbet M Peeters, Lotte Geys, Tina Parciak, Anne Helme, Jan Hillert, Yves Moreau, Gilles Edan, Tim Spelman, Sifat Sharmin, Robert McBurney, Hollie Schmidt, Arnfin Bergmann, Stefan Braune, Alexander Stahmann, Rodden Middleton, Amber Salter, Bruce Bebo, Anneke van der Walt, Helmut Butzkueven, Serkan Ozakbas, Rana Karabudak, Cavit Boz, Raed Alroughani, Juan I Rojas, Ingrid van der Mei, Guilherme Sciascia do Olival, Melinda Magyari, Ricardo Alonso, Richard Nicholas, Anibal Chertcoff, Ana Zabalza, Georgina Arrambide, Nupur Nag, Annabel Descamps, Lars Costers, Ruth Dobson, Aleisha Miller, Paulo Rodrigues, Vesna Prčkovska, Giancarlo Comi, Tomas Kalincik
Mult Scler Relat Disord. 2022 Oct;66:104072. doi: 10.1016/j.msard.2022.104072. Epub 2022 Jul 25.
Multiple Sclerosis Relapses Following Cessation of Fingolimod
Charles B Malpas, Izanne Roos, Sifat Sharmin, Katherine Buzzard, Olga Skibina, Helmut Butzkueven, Ludwig Kappos, Francesco Patti, Raed Alroughani, Dana Horakova, Eva Kubala Havrdova, Guillermo Izquierdo, Sara Eichau, Suzanne Hodgkinson, Pierre Grammond, Jeannette Lechner-Scott, Tomas Kalincik, MSBase Study Group
Clin Drug Investig. 2022 Apr;42(4):355-364. doi: 10.1007/s40261-022-01129-7. Epub 2022 Mar 18.
A stochastic model for early identification of infectious disease epidemics with application to measles cases in Bangladesh
Sifat Sharmin, Md Israt Rayhan
Asia Pac J Public Health. 2015 Mar;27(2):NP816-23. doi: 10.1177/1010539512461668. Epub 2012 Nov 18.
Modelling of infectious diseases for providing signal of epidemics: a measles case study in Bangladesh
Sifat Sharmin, Israt Rayhan
J Health Popul Nutr. 2011 Dec;29(6):567-73. doi: 10.3329/jhpn.v29i6.9893.