Introducing

Dr Sifat Sharmin

Hello, I’m Sifat, a Biostatistician and Research Stream Leader (Multiple Sclerosis) in the Clinical Outcomes Research (CORe) Unit.

Dr Sifat Sharmin

Biostatistician & Research Fellow (Multiple Sclerosis)

PhD (Biostatistics), MSc & BSc (Honours) in Applied Statistics

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a little bit about me

I am a biostatistician with experience in the analysis of large-scale data, including longitudinal survey and administrative data and modelling of count and longitudinal time-to-event data.

My current research interest is the application and extension of complex statistical methods to understand the clinical dynamics of multiple sclerosis (MS) and compare treatment outcomes in MS patients.

I have taught biostatistics and epidemiology to graduate students at The Australian National University and The University of Melbourne.

Publications

Utilization of Multiple Sclerosis Therapies in the Middle East Over a Decade: 2009-2018
Nahid Moradi, Sifat Sharmin, Charles Malpas, Serkan Ozakbas, Vahid Shaygannejad, Murat Terzi, Cavit Boz, Bassem Yamout, Recai Turkoglu, Rana Karabudak, Sherif Hamdy, Aysun Soysal, Ayşe Altıntaş, Jihad Inshasi, Talal Al-Harbi, Raed Alroughani, Tomas Kalincik, MSBase Study Group
CNS Drugs. 2021 Jun 23. doi: 10.1007/s40263-021-00833-w. Online ahead of print.

The effectiveness of natalizumab vs fingolimod-A comparison of international registry studies
Johanna B Andersen, Sifat Sharmin, Mathilde Lefort, Nils Koch-Henriksen, Finn Sellebjerg, Per Soelberg Sørensen, Claudia C Hilt Christensen, Peter V Rasmussen, Michael B Jensen, Jette L Frederiksen, Stephan Bramow, Henrik K Mathiesen, Karen I Schreiber, Dana Horakova, Eva K Havrdova, Raed Alroughani, Guillermo Izquierdo, Sara Eichau, Serkan Ozakbas, Francesco Patti, Marco Onofrj, Alessandra Lugaresi, Murat Terzi, Pierre Grammond, Francois Grand Maison, Bassem Yamout, Alexandre Prat, Marc Girard, Pierre Duquette, Cavit Boz, Maria Trojano, Pamela McCombe, Mark Slee, Jeannette Lechner-Scott, Recai Turkoglu, Patrizia Sola, Diana Ferraro, Franco Granella, Vahid Shaygannejad, Julie Prevost, Olga Skibina, Claudio Solaro, Rana Karabudak, Bart V Wijmeersch, Tunde Csepany, Daniele Spitaleri, Steve Vucic, Romain Casey, Marc Debouverie, Gilles Edan, Jonathan Ciron, Aurélie Ruet, Jérôme D Sèze, Elisabeth Maillart, Hélène Zephir, Pierre Labauge, Gilles Defer, Christine Lebrun, Thibault Moreau, Eric Berger, Pierre Clavelou, Jean Pelletier, Bruno Stankoff, Olivier Gout, Eric Thouvenot, Olivier Heinzlef, Abdullatif Al-Khedr, Bertrand Bourre, Olivier Casez, Philippe Cabre, Alexis Montcuquet, Abir Wahab, Jean-Philippe Camdessanché, Aude Marousset, Ivania Patry, Karolina Hankiewicz, Corinne Pottier, Nicolas Maubeuge, Céline Labeyrie, Chantal Nifle, Emmanuelle Leray, David A Laplaud, Helmut Butzkueven, Tomas Kalincik, Sandra Vukusic, Melinda Magyari
Mult Scler Relat Disord. 2021 Aug;53:103012. doi: 10.1016/j.msard.2021.103012. Epub 2021 May 8.

Predicting all-cause unplanned readmission within 30 days of discharge using electronic medical record data: A multi-centre study
Sifat Sharmin, Johannes J Meij, Jeffrey D Zajac, Alan Rob Moodie, Andrea B Maier
Int J Clin Pract. 2021 Aug;75(8):e14306. doi: 10.1111/ijcp.14306. Epub 2021 May 17.

Predicting Infection Risk in Multiple Sclerosis Patients Treated with Ocrelizumab: A Retrospective Cohort Study
Nabil Seery, Sifat Sharmin, Vivien Li, Ai-Lan Nguyen, Claire Meaton, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Mark P Marriott, Katherine A Buzzard, Izanne Roos, Chris Dwyer, Josephine Baker, Lisa Taylor, Kymble Spriggs, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
CNS Drugs. 2021 Aug;35(8):907-918. doi: 10.1007/s40263-021-00810-3. Epub 2021 Apr 13.

Effect of Disease-Modifying Therapy on Disability in Relapsing-Remitting Multiple Sclerosis Over 15 Years
Tomas Kalincik, Ibrahima Diouf, Sifat Sharmin, Charles Malpas, Tim Spelman, Dana Horakova, Eva Kubala Havrdova, Maria Trojano, Guillermo Izquierdo, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Vilija Jokubaitis, Anneke van der Walt, Francois Grand'Maison, Patrizia Sola, Diana Ferraro, Vahid Shaygannejad, Raed Alroughani, Raymond Hupperts, Murat Terzi, Cavit Boz, Jeannette Lechner-Scott, Eugenio Pucci, Vincent Van Pesch, Franco Granella, Roberto Bergamaschi, Daniele Spitaleri, Mark Slee, Steve Vucic, Radek Ampapa, Pamela McCombe, Cristina Ramo-Tello, Julie Prevost, Javier Olascoaga, Edgardo Cristiano, Michael Barnett, Maria Laura Saladino, Jose Luis Sanchez-Menoyo, Suzanne Hodgkinson, Csilla Rozsa, Stella Hughes, Fraser Moore, Cameron Shaw, Ernest Butler, Olga Skibina, Orla Gray, Allan Kermode, Tunde Csepany, Bhim Singhal, Neil Shuey, Imre Piroska, Bruce Taylor, Magdolna Simo, Carmen-Adella Sirbu, Attila Sas, Helmut Butzkueven, MSBase Study Group
Neurology. 2021 Feb 2;96(5):e783-e797. doi: 10.1212/WNL.0000000000011242. Epub 2020 Dec 28.

Association of Sustained Immunotherapy With Disability Outcomes in Patients With Active Secondary Progressive Multiple Sclerosis
Nathaniel Lizak, Charles B Malpas, Sifat Sharmin, Eva Kubala Havrdova, Dana Horakova, Guillermo Izquierdo, Sara Eichau, Alessandra Lugaresi, Pierre Duquette, Marc Girard, Alexandre Prat, Catherine Larochelle, Maria Trojano, Francois Grand'Maison, Pierre Grammond, Patrizia Sola, Diana Ferraro, Raymond Hupperts, Roberto Bergamaschi, Cavit Boz, Vincent Van Pesch, Daniele Spitaleri, Murat Terzi, Tomas Kalincik, MSBase Study Group
JAMA Neurol. 2020 Nov 1;77(11):1398-1407. doi: 10.1001/jamaneurol.2020.2453.

Disability outcomes of early cerebellar and brainstem symptoms in multiple sclerosis
Minh Le, Charles Malpas, Sifat Sharmin, Dana Horáková, Eva Havrdova, Maria Trojano, Guillermo Izquierdo, Sara Eichau, Serkan Ozakbas, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Catherine Larochelle, Raed Alroughani, Roberto Bergamaschi, Patrizia Sola, Diana Ferraro, Pierre Grammond, Francois Grand' Maison, Murat Terzi, Cavit Boz, Raymond Hupperts, Helmut Butzkueven, Eugenio Pucci, Franco Granella, Vincent Van Pesch, Aysun Soysal, Bassem I Yamout, Jeannette Lechner-Scott, Daniele LA Spitaleri, Radek Ampapa, Recai Turkoglu, Gerardo Iuliano, Cristina Ramo-Tello, Jose Luis Sanchez-Menoyo, Youssef Sidhom, Riadh Gouider, Vahid Shaygannejad, Julie Prevost, Ayse Altintas, Yara Dadalti Fragoso, Pamela Ann McCombe, Thor Petersen, Mark Slee, Michael H Barnett, Steve Vucic, Anneke Van Der Walt, Tomas Kalincik
Mult Scler. 2021 Apr;27(5):755-766. doi: 10.1177/1352458520926955. Epub 2020 Jun 15.

Early clinical markers of aggressive multiple sclerosis
Charles B Malpas, Ali Manouchehrinia, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Maria Trojano, Guillermo Izquierdo, Sara Eichau, Roberto Bergamaschi, Patrizia Sola, Diana Ferraro, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Francois Grand'Maison, Serkan Ozakbas, Vincent Van Pesch, Franco Granella, Raymond Hupperts, Eugenio Pucci, Cavit Boz, Youssef Sidhom, Riadh Gouider, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Freek Verheul, Rana Karabudak, Recai Turkoglu, Cristina Ramo-Tello, Murat Terzi, Edgardo Cristiano, Mark Slee, Pamela McCombe, Richard Macdonell, Yara Fragoso, Javier Olascoaga, Ayse Altintas, Tomas Olsson, Helmut Butzkueven, Jan Hillert, Tomas Kalincik
Brain. 2020 May 1;143(5):1400-1413. doi: 10.1093/brain/awaa081.

Trajectories of Mini-Mental State Examination Scores over the Lifespan in General Populations: A Systematic Review and Meta-Regression Analysis
Julius M Nagaratnam, Sifat Sharmin, Aaron Diker, Wen Kwang Lim, Andrea B Maier
Clin Gerontol. 2020 May 6:1-10. doi: 10.1080/07317115.2020.1756021. Online ahead of print.

The histopathological staging of tau, but not amyloid, corresponds to antemortem cognitive status, dementia stage, functional abilities and neuropsychiatric symptoms
Charles B Malpas, Sifat Sharmin, Tomas Kalincik
Int J Neurosci. 2021 Aug;131(8):800-809. doi: 10.1080/00207454.2020.1758087. Epub 2020 Apr 30.

Timing of high-efficacy therapy for multiple sclerosis: a retrospective observational cohort study
Anna He, Bernd Merkel, James William L Brown, Lana Zhovits Ryerson, Ilya Kister, Charles B Malpas, Sifat Sharmin, Dana Horakova, Eva Kubala Havrdova, Tim Spelman, Guillermo Izquierdo, Sara Eichau, Maria Trojano, Alessandra Lugaresi, Raymond Hupperts, Patrizia Sola, Diana Ferraro, Jan Lycke, Francois Grand'Maison, Alexandre Prat, Marc Girard, Pierre Duquette, Catherine Larochelle, Anders Svenningsson, Thor Petersen, Pierre Grammond, Franco Granella, Vincent Van Pesch, Roberto Bergamaschi, Christopher McGuigan, Alasdair Coles, Jan Hillert, Fredrik Piehl, Helmut Butzkueven, Tomas Kalincik, MSBase study group
Lancet Neurol. 2020 Apr;19(4):307-316. doi: 10.1016/S1474-4422(20)30067-3. Epub 2020 Mar 18.

Orthostatic hypotension and cognition in older adults: A systematic review and meta-analysis
Rebecca Iseli, Vi Truc Vo Nguyen, Sifat Sharmin, Esmee M Reijnierse, Wen Kwang Lim, Andrea B Maier
Exp Gerontol. 2019 Jun;120:40-49. doi: 10.1016/j.exger.2019.02.017. Epub 2019 Feb 28.

Orthostatic Hypotension and Falls in Older Adults: A Systematic Review and Meta-analysis
Arjen Mol, Phuong Thanh Silvie Bui Hoang, Sifat Sharmin, Esmee M Reijnierse, Richard J A van Wezel, Carel G M Meskers, Andrea B Maier
J Am Med Dir Assoc. 2019 May;20(5):589-597.e5. doi: 10.1016/j.jamda.2018.11.003. Epub 2018 Dec 21.

Geostatistical mapping of the seasonal spread of under-reported dengue cases in Bangladesh
Sifat Sharmin, Kathryn Glass, Elvina Viennet, David Harley
PLoS Negl Trop Dis. 2018 Nov 15;12(11):e0006947. doi: 10.1371/journal.pntd.0006947. eCollection 2018 Nov.

Comparing indigenous mortality across urban, rural and very remote areas: a systematic review and meta-analysis
Edward Carson, Sifat Sharmin, Andrea B Maier, Johannes J Meij
Int Health. 2018 Jul 1;10(4):219-227. doi: 10.1093/inthealth/ihy021.

A Bayesian approach for estimating under-reported dengue incidence with a focus on non-linear associations between climate and dengue in Dhaka, Bangladesh
Sifat Sharmin, Kathryn Glass, Elvina Viennet, David Harley
Stat Methods Med Res. 2018 Apr;27(4):991-1000. doi: 10.1177/0962280216649216. Epub 2016 May 13.

The emergence of dengue in Bangladesh: epidemiology, challenges and future disease risk
Sifat Sharmin, Elvina Viennet, Kathryn Glass, David Harley
Trans R Soc Trop Med Hyg. 2015 Oct;109(10):619-27. doi: 10.1093/trstmh/trv067. Epub 2015 Sep 1.

Interaction of Mean Temperature and Daily Fluctuation Influences Dengue Incidence in Dhaka, Bangladesh
Sifat Sharmin, Kathryn Glass, Elvina Viennet, David Harley
PLoS Negl Trop Dis. 2015 Jul 10;9(7):e0003901. doi: 10.1371/journal.pntd.0003901. eCollection 2015.

A stochastic model for early identification of infectious disease epidemics with application to measles cases in Bangladesh
Sifat Sharmin, Md Israt Rayhan
Asia Pac J Public Health. 2015 Mar;27(2):NP816-23. doi: 10.1177/1010539512461668. Epub 2012 Nov 18.

Profile: the Chakaria Health and Demographic Surveillance System
Manzoor Ahmed Hanifi, Abdullah Al Mamun, Ashish Paul, Sharif Al Hasan, Shahidul Hoque, Sifat Sharmin, Farhana Urni, Imran Reza Khan, Shehrin Shaila Mahmood, Sabrina Rasheed, Mohammad Iqbal, Ariful Moula, Mijanur Rahman, Abbas Bhuiya
Int J Epidemiol. 2012 Jun;41(3):667-75. doi: 10.1093/ije/dys089.

Modelling of infectious diseases for providing signal of epidemics: a measles case study in Bangladesh
Sifat Sharmin, Israt Rayhan
J Health Popul Nutr. 2011 Dec;29(6):567-73. doi: 10.3329/jhpn.v29i6.9893.