Introducing

Prof Tomas Kalincik

Hello, I’m Tomas, Head of the Clinical Outcomes Research (CORe) Unit.

TK Profile

Prof Tomas Kalincik

Group Leader, Head of Neuroimmunology & MS at RMH

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P: +61 3 9342 4404

a little bit about me

I am the Head of the CORe Unit at the University of Melbourne, as well as the Head of the Multiple Sclerosis and Neuroimmunology Service at The Royal Melbourne Hospital.

Together with the CORe team, I specialise in analytics of observational data in neurology. I am an active participant in the global MSBase collaboration, undertaking a role in the MSBase Scientific Leadership Group.

My research interests revolve around disease outcomes in Multiple Sclerosis and Neuromyelitis Optica. These comprise comparative treatment effectiveness, management of treatment failure, individual treatment response, personalised therapy, prognostics, epidemiology and utility of volumetric MRI.

Publications

Oral corticosteroid dosage and taper duration at onset in myelin oligodendrocyte glycoprotein antibody-associated disease influences time to first relapse
Benjamin P Trewin, Russell C Dale, Jessica Qiu, Melissa Chu, Niroshan Jeyakumar, Fionna Dela Cruz, Jane Andersen, Pakeeran Siriratnam, Kit Kwan M Ma, Todd A Hardy, Anneke van der Walt, Jeanette Lechner-Scott, Helmut Butzkueven, Simon A Broadley, Michael H Barnett, Stephen W Reddel, Fabienne Brilot, Tomas Kalincik, Sudarshini Ramanathan, Australasian MOGAD Study Group
J Neurol Neurosurg Psychiatry. 2024 May 16:jnnp-2024-333463. doi: 10.1136/jnnp-2024-333463. Online ahead of print.

Escalating to medium- versus high-efficacy disease modifying therapy after low-efficacy treatment in relapsing remitting multiple sclerosis
Jannis Müller, Izanne Roos, Tomas Kalincik, Johannes Lorscheider, Edoardo Galli, Pascal Benkert, Sabine Schädelin, Sifat Sharmin, Maximilian Einsiedler, Peter Hänni, Jürg Schmid, Jens Kuhle, Tobias Derfuss, Cristina Granziera, Tjalf Ziemssen, Timo Siepmann, Özgür Yaldizli
Brain Behav. 2024 May;14(5):e3498. doi: 10.1002/brb3.3498.

Postural behaviour in people with multiple sclerosis: A complexity paradox
L Eduardo Cofré Lizama, Maya G Panisset, Liuhua Peng, Ying Tan, Tomas Kalincik, Mary P Galea
Gait Posture. 2024 Mar 27;111:14-21. doi: 10.1016/j.gaitpost.2024.03.013. Online ahead of print.

Routine CSF parameters as predictors of disease course in multiple sclerosis: an MSBase cohort study
Cathérine Dekeyser, Matthias Hautekeete, Melissa Cambron, Vincent Van Pesch, Francesco Patti, Jens Kuhle, Samia Khoury, Jeanette Lechner Scott, Oliver Gerlach, Alessandra Lugaresi, Davide Maimone, Andrea Surcinelli, Pierre Grammond, Tomas Kalincik, Mario Habek, Barbara Willekens, Richard Macdonell, Patrice Lalive, Tunde Csepany, Helmut Butzkueven, Cavit Boz, Valentina Tomassini, Matteo Foschi, José Luis Sánchez-Menoyo, Ayse Altintas, Saloua Mrabet, Gerardo Iuliano, Maria Jose Sa, Raed Alroughani, Rana Karabudak, Eduardo Aguera-Morales, Orla Gray, Koen de Gans, Anneke van der Walt, Pamela A McCombe, Norma Deri, Justin Garber, Abdullah Al-Asmi, Olga Skibina, Pierre Duquette, Elisabetta Cartechini, Daniele Spitaleri, Riadh Gouider, Aysun Soysal, Liesbeth Van Hijfte, Mark Slee, Maria Pia Amato, Katherine Buzzard, Guy Laureys
J Neurol Neurosurg Psychiatry. 2024 Apr 3:jnnp-2023-333307. doi: 10.1136/jnnp-2023-333307. Online ahead of print.

Disease-modifying therapies in managing disability worsening in paediatric-onset multiple sclerosis: a longitudinal analysis of global and national registries
Sifat Sharmin, Izanne Roos, Charles B Malpas, Pietro Iaffaldano, Marta Simone, Massimo Filippi, Eva Kubala Havrdova, Serkan Ozakbas, Vincenzo Brescia Morra, Raed Alroughani, Mauro Zaffaroni, Francesco Patti, Sara Eichau, Giuseppe Salemi, Alessia Di Sapio, Matilde Inglese, Emilio Portaccio, Maria Trojano, Maria Pia Amato, Tomas Kalincik, Writing Group, Italian Multiple Sclerosis and Related Disorders Register and MSBase Study Group
Lancet Child Adolesc Health. 2024 May;8(5):348-357. doi: 10.1016/S2352-4642(24)00047-6. Epub 2024 Mar 25.

Effectiveness of autologous haematopoietic stem cell transplantation versus natalizumab in progressive multiple sclerosis
Tomas Kalincik, Sifat Sharmin, Izanne Roos, Jennifer Massey, Ian Sutton, Barbara Withers, Mark S Freedman, Harold Atkins, Eva Krasulova, Eva Kubala Havrdova, Marek Trneny, Tomas Kozak, Joachim Burman, Richard Macdonell, Øivind Torkildsen, Lars Bø, Anne Kristine Lehmann, Basil Sharrack, John Snowden
J Neurol Neurosurg Psychiatry. 2024 Mar 27:jnnp-2023-332790. doi: 10.1136/jnnp-2023-332790. Online ahead of print.

Comparing ocrelizumab to interferon/glatiramer acetate in people with multiple sclerosis over age 60
Yi Chao Foong, Daniel Merlo, Melissa Gresle, Katherine Buzzard, Michael Zhong, Wei Zhen Yeh, Vilija Jokubaitis, Mastura Monif, Olga Skibina, Serkan Ozakbas, Francesco Patti, Pierre Grammond, Maria Pia Amato, Tomas Kalincik, Dana Horakova, Eva Kubala Havrdova, Bianca Weinstock-Guttman, Jeanette Lechner Scott, Cavit Boz, Maria Jose Sa, Helmut Butzkueven, Anneke van der Walt, Chao Zhu, MSBASE study group
J Neurol Neurosurg Psychiatry. 2024 Mar 7:jnnp-2023-332883. doi: 10.1136/jnnp-2023-332883. Online ahead of print.

Long-term clinical outcomes in patients with multiple sclerosis who are initiating disease-modifying therapy with natalizumab compared with BRACETD first-line therapies
Helmut Butzkueven, Tomas Kalincik, Francesco Patti, Mark Slee, Bianca Weinstock-Guttman, Katherine Buzzard, Olga Skibina, Raed Alroughani, Alexandre Prat, Marc Girard, Dana Horakova, Eva Kubala Havrdova, Anneke Van der Walt, Sara Eichau, Robert Hyde, Nolan Campbell, Karthik Bodhinathan, Tim Spelman, MSBase Investigators
Ther Adv Neurol Disord. 2024 Feb 26;17:17562864231221331. doi: 10.1177/17562864231221331. eCollection 2024.

Language impairments in seropositive and seronegative autoimmune encephalitis
Sarah P Griffith, Robb Wesselingh, Fiore D'Aprano, Nabil Seery, Tiffany Rushen, Chris Kyndt, Brian Long, Udaya Seneviratne, Tomas Kalincik, Katherine Buzzard, Helmut Butzkueven, Terence J O'Brien, Rubina Alpitsis, Charles B Malpas, Mastura Monif, Australian Autoimmune Encephalitis Consortium
Neurol Sci. 2024 Feb 15. doi: 10.1007/s10072-024-07382-2. Online ahead of print.

Sample Entropy Improves Assessment of Postural Control in Early-Stage Multiple Sclerosis
L Eduardo Cofré Lizama, Xiangyu He, Tomas Kalincik, Mary P Galea, Maya G Panisset
Sensors (Basel). 2024 Jan 29;24(3):872. doi: 10.3390/s24030872.

Risk of Cervical Abnormalities for Women With Multiple Sclerosis Treated With Moderate-Efficacy and High-Efficacy Disease-Modifying Therapies
Francesca Bridge, Julia Brotherton, Jim Stankovich, Paul G Sanfilippo, Olga G Skibina, Katherine Buzzard, Tomas Kalincik, Ai-Lan Nguyen, Kylie Guo, Mastura Monif, C David Wrede, Louise Rath, Lisa Taylor, Helmut Butzkueven, Vilija G Jokubaitis, Anneke Van Der Walt
Neurology. 2024 Feb;102(4):e208059. doi: 10.1212/WNL.0000000000208059. Epub 2024 Feb 2.

The MOG antibody non-P42 epitope is predictive of a relapsing course in MOG antibody-associated disease
Ganesha Liyanage, Benjamin P Trewin, Joseph A Lopez, Jane Andersen, Fiona Tea, Vera Merheb, Kristy Nguyen, Fiona X Z Lee, Marzena J Fabis-Pedrini, Alicia Zou, Ali Buckland, Anthony Fok, Michael H Barnett, Stephen W Reddel, Romain Marignier, Aseel El Hajj, Mastura Monif, Anneke van der Walt, Jeannette Lechner-Scott, Allan G Kermode, Tomas Kalincik, Simon A Broadley, Russell C Dale, Sudarshini Ramanathan, Fabienne Brilot, on behalf the Australasian MOGAD Study Group
J Neurol Neurosurg Psychiatry. 2024 May 14;95(6):544-553. doi: 10.1136/jnnp-2023-332851.

Emulating randomised clinical trials in relapsing-remitting multiple sclerosis with non-randomised real-world evidence: an application using data from the MSBase Registry
Alessio Signori, Marta Ponzano, Tomas Kalincik, Serkan Ozakbas, Dana Horakova, Eva Kubala Havrdova, Raed Alroughani, Francesco Patti, Jens Kuhle, Guillermo Izquierdo, Sara Eichau, Bassem Yamout, Samia Joseph Khoury, Rana Karabudak, Pierre Grammond, Pierre Duquette, Izanne Roos, Helmut Butzkueven, Anneke van der Walt, Maria Pia Sormani
J Neurol Neurosurg Psychiatry. 2024 Jan 19:jnnp-2023-332603. doi: 10.1136/jnnp-2023-332603. Online ahead of print.

Predictors of treatment switching in the Big Multiple Sclerosis Data Network
Tim Spelman, Melinda Magyari, Helmut Butzkueven, Anneke Van Der Walt, Sandra Vukusic, Maria Trojano, Pietro Iaffaldano, Dana Horáková, Jirí Drahota, Fabio Pellegrini, Robert Hyde, Pierre Duquette, Jeannette Lechner-Scott, Seyed Aidin Sajedi, Patrice Lalive, Vahid Shaygannejad, Serkan Ozakbas, Sara Eichau, Raed Alroughani, Murat Terzi, Marc Girard, Tomas Kalincik, Francois Grand'Maison, Olga Skibina, Samia J Khoury, Bassem Yamout, Maria Jose Sa, Oliver Gerlach, Yolanda Blanco, Rana Karabudak, Celia Oreja-Guevara, Ayse Altintas, Stella Hughes, Pamela McCombe, Radek Ampapa, Koen de Gans, Chris McGuigan, Aysun Soysal, Julie Prevost, Nevin John, Jihad Inshasi, Leszek Stawiarz, Ali Manouchehrinia, Lars Forsberg, Finn Sellebjerg, Anna Glaser, Luigi Pontieri, Hanna Joensen, Peter Vestergaard Rasmussen, Tobias Sejbaek, Mai Bang Poulsen, Jeppe Romme Christensen, Matthias Kant, Morten Stilund, Henrik Mathiesen, Jan Hillert, Big MS Data Network: a collaboration of the Czech MS Registry, the Danish MS Registry, Italian MS Registry, Swedish MS Registry, MSBase Study Group, and OFSEP
Front Neurol. 2023 Dec 22;14:1274194. doi: 10.3389/fneur.2023.1274194. eCollection 2023.

Comparative effectiveness and cost-effectiveness of natalizumab and fingolimod in rapidly evolving severe relapsing-remitting multiple sclerosis in the United Kingdom
T Spelman, W L Herring, C Acosta, R Hyde, V G Jokubaitis, E Pucci, A Lugaresi, G Laureys, E K Havrdova, D Horakova, G Izquierdo, S Eichau, S Ozakbas, R Alroughani, T Kalincik, P Duquette, M Girard, T Petersen, F Patti, T Csepany, F Granella, F Grand'Maison, D Ferraro, R Karabudak, M Jose Sa, M Trojano, V van Pesch, B Van Wijmeersch, E Cartechini, P McCombe, O Gerlach, D Spitaleri, C Rozsa, S Hodgkinson, R Bergamaschi, R Gouider, A Soysal, None Castillo-Triviño, J Prevost, J Garber, K de Gans, R Ampapa, M Simo, J L Sanchez-Menoyo, G Iuliano, A Sas, A van der Walt, N John, O Gray, S Hughes, G De Luca, M Onofrj, K Buzzard, O Skibina, M Terzi, M Slee, C Solaro, None Oreja-Guevara, C Ramo-Tello, Y Fragoso, V Shaygannejad, F Moore, C Rajda, E Aguera Morales, H Butzkueven
J Med Econ. 2024 Jan-Dec;27(1):109-125. doi: 10.1080/13696998.2023.2293379. Epub 2023 Dec 26.

Patterns of neurotoxicity among patients receiving chimeric antigen receptor T-cell therapy: A single-centre cohort study
Carmela Sales, Mary Ann Anderson, Valeriya Kuznetsova, Hannah Rosenfeld, Charles B Malpas, Izanne Roos, Michael Dickinson, Simon Harrison, Tomas Kalincik
Eur J Neurol. 2024 Mar;31(3):e16174. doi: 10.1111/ene.16174. Epub 2023 Dec 12.

Vitamin D did not reduce multiple sclerosis disease activity after a clinically isolated syndrome
Helmut Butzkueven, Anne-Louise Ponsonby, Mark S Stein, Robyn M Lucas, Deborah Mason, Simon Broadley, Trevor Kilpatrick, Jeannette Lechner-Scott, Michael Barnett, William Carroll, Peter Mitchell, Todd A Hardy, Richard Macdonell, Pamela McCombe, Andrew Lee, Tomas Kalincik, Anneke van der Walt, Chris Lynch, David Abernethy, Ernest Willoughby, Frederik Barkhof, David MacManus, Michael Clarke, Julie Andrew, Julia Morahan, Chao Zhu, Keith Dear, Bruce V Taylor, PREVANZ Investigators
Brain. 2024 Apr 4;147(4):1206-1215. doi: 10.1093/brain/awad409.

How effective is effective enough?
Tomas Kalincik, Amy Brodtmann
J Neurol Neurosurg Psychiatry. 2023 Dec 14;95(1):1. doi: 10.1136/jnnp-2023-332311.

Comparative Efficacy of Disease-Modifying Treatments for Relapsing Multiple Sclerosis-Variations in Real-World Experience-Reply
Izanne Roos, Tomas Kalincik
JAMA Neurol. 2024 Jan 1;81(1):87-88. doi: 10.1001/jamaneurol.2023.4392.

Leveraging Real-World Evidence and Observational Studies in Treating Multiple Sclerosis
Albert Aboseif, Izanne Roos, Stephen Krieger, Tomas Kalincik, Carrie M Hersh
Neurol Clin. 2024 Feb;42(1):203-227. doi: 10.1016/j.ncl.2023.06.003. Epub 2023 Jul 21.

Methodological considerations for observational studies of treatment effectiveness in neurology: a clinician's guide
Tomas Kalincik, Izanne Roos, Sifat Sharmin, Charles B Malpas
J Neurol Neurosurg Psychiatry. 2024 Apr 12;95(5):454-460. doi: 10.1136/jnnp-2022-330038.

Examining the environmental risk factors of progressive-onset and relapsing-onset multiple sclerosis: recruitment challenges, potential bias, and statistical strategies
Ying Li, Alice Saul, Bruce Taylor, Anne-Louise Ponsonby, Steve Simpson-Yap, Leigh Blizzard, Simon Broadley, Jeannette Lechner-Scott, Ausimmune/AusLong Investigators Group, Rana Karabudak, Francesco Patti, Sara Eichau, Marco Onofrj, Serkan Ozakbas, Dana Horakova, Eva Kubala Havrdova, Francois Grand'Maison, Raed Alroughani, Oliver Gerlach, Maria Pia Amato, Ayse Altintas, Marc Girard, Pierre Duquette, Yolanda Blanco, Cristina Ramo-Tello, Guy Laureys, Tomas Kalincik, Samia J Khoury, Vahid Shaygannejad, Masoud Etemadifar, Bhim Singhal, Saloua Mrabet, Matteo Foschi, Mario Habek, Nevin John, Stella Hughes, Pamela McCombe, Radek Ampapa, Anneke van der Walt, Helmut Butzkueven, Koen de Gans, Chris McGuigan, Celia Oreja-Guevara, Maria Jose Sa, Thor Petersen, Talal Al-Harbi, Angel Perez Sempere, Bart Van Wijmeersch, Nikolaos Grigoriadis, Julie Prevost, Orla Gray, Tamara Castillo-Triviño, Richard Macdonell, Alessandra Lugaresi, Seyed Aidin Sajedi, MSBase, Ingrid van der Mei
J Neurol. 2024 Jan;271(1):472-485. doi: 10.1007/s00415-023-11980-z. Epub 2023 Sep 28.

Rates of John Cunningham virus seroconversion greatly reduced in natalizumab-treated patients during COVID-19-related lockdowns
Chris Dwyer, Sifat Sharmin, Tomas Kalincik
Eur J Neurol. 2024 Jan;31(1):e16059. doi: 10.1111/ene.16059. Epub 2023 Sep 14.

Literature Commentary

J Neuroophthalmol. 2021 Mar 1;41(1):128-134. doi: 10.1097/WNO.0000000000001201. Epub 2021 Jan 22.

Observational studies of treatment effectiveness in neurology
Tomas Kalincik, Izanne Roos, Sifat Sharmin
Brain. 2023 Dec 1;146(12):4799-4808. doi: 10.1093/brain/awad278.

The Patient-Determined Disease Steps scale is not interchangeable with the Expanded Disease Status Scale in mild to moderate multiple sclerosis
Yi Chao Foong, Daniel Merlo, Melissa Gresle, Chao Zhu, Katherine Buzzard, Jeannette Lechner-Scott, Michael Barnett, Bruce Taylor, Tomas Kalincik, Trevor Kilpatrick, David Darby, Pamela Dobay, Johan van Beek, Robert Hyde, Helmut Butzkueven, Anneke van der Walt
Eur J Neurol. 2024 Jan;31(1):e16046. doi: 10.1111/ene.16046. Epub 2023 Aug 24.

Plasma neurofilament light in behavioural variant frontotemporal dementia compared to mood and psychotic disorders
Dhamidhu Eratne, Matthew Kang, Charles Malpas, Steve Simpson-Yap, Courtney Lewis, Christa Dang, Jasleen Grewal, Amy Coe, Hannah Dobson, Michael Keem, Wei-Hsuan Chiu, Tomas Kalincik, Suyi Ooi, David Darby, Amy Brodtmann, Oskar Hansson, Shorena Janelidze, Kaj Blennow, Henrik Zetterberg, Adam Walker, Olivia Dean, Michael Berk, Cassandra Wannan, Christos Pantelis, Samantha M Loi, Mark Walterfang, Samuel F Berkovic, Alexander F Santillo, Dennis Velakoulis
Aust N Z J Psychiatry. 2024 Jan;58(1):70-81. doi: 10.1177/00048674231187312. Epub 2023 Jul 21.

Early Treatment for Multiple Sclerosis: Time Is Brain
Erin E Longbrake, Tomas Kalincik
Neurology. 2023 Sep 26;101(13):549-550. doi: 10.1212/WNL.0000000000207754. Epub 2023 Jul 19.

Longitudinal epidemiology of multiple sclerosis in Townsville, Queensland, Australia, 2012-2022
Steve Simpson-Yap, Duncan Maddox, Jeanette Reece, Jeannette Lechner-Scott, Cameron Shaw, Bruce Taylor, Tomas Kalincik, Anneke van der Walt, Mike Boggild
Mult Scler Relat Disord. 2023 Sep;77:104845. doi: 10.1016/j.msard.2023.104845. Epub 2023 Jun 28.

Comparative Effectiveness of Autologous Hematopoietic Stem Cell Transplant vs Fingolimod, Natalizumab, and Ocrelizumab in Highly Active Relapsing-Remitting Multiple Sclerosis
Tomas Kalincik, Sifat Sharmin, Izanne Roos, Mark S Freedman, Harold Atkins, Joachim Burman, Jennifer Massey, Ian Sutton, Barbara Withers, Richard Macdonell, Andrew Grigg, Øivind Torkildsen, Lars Bo, Anne Kristine Lehmann, Eva Kubala Havrdova, Eva Krasulova, Marek Trnený, Tomas Kozak, Anneke van der Walt, Helmut Butzkueven, Pamela McCombe, Olga Skibina, Jeannette Lechner-Scott, Barbara Willekens, Elisabetta Cartechini, Serkan Ozakbas, Raed Alroughani, Jens Kuhle, Francesco Patti, Pierre Duquette, Alessandra Lugaresi, Samia J Khoury, Mark Slee, Recai Turkoglu, Suzanne Hodgkinson, Nevin John, Davide Maimone, Maria Jose Sa, Vincent van Pesch, Oliver Gerlach, Guy Laureys, Liesbeth Van Hijfte, Rana Karabudak, Daniele Spitaleri, Tunde Csepany, Riadh Gouider, Tamara Castillo-Triviño, Bruce Taylor, Basil Sharrack, John A Snowden, MSBase Study Group Collaborators, MSBase Study Group Authors, Saloua Mrabet, Justin Garber, Jose Luis Sanchez-Menoyo, Eduardo Aguera-Morales, Yolanda Blanco, Abdullah Al-Asmi, Bianca Weinstock-Guttman, Yara Fragoso, Koen de Gans, Allan Kermode, MSBase Study Group
JAMA Neurol. 2023 Jul 1;80(7):702-713. doi: 10.1001/jamaneurol.2023.1184.

Risk of secondary progressive multiple sclerosis after early worsening of disability
Winston Dzau, Sifat Sharmin, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Alexandre Prat, Marc Girard, Pierre Duquette, Marco Onofrj, Alessandra Lugaresi, Serkan Ozakbas, Oliver Gerlach, Cavit Boz, Pierre Grammond, Murat Terzi, Maria Pia Amato, Daniele La Spitaleri, Cristina Ramo-Tello, Davide Maimone, Elisabetta Cartechini, Katherine Buzzard, Olga Skibina, Anneke van der Walt, Helmut Butzkueven, Gerardo Iuliano, Aysun Soysal, Tomas Kalincik
J Neurol Neurosurg Psychiatry. 2023 Dec;94(12):984-991. doi: 10.1136/jnnp-2023-331748. Epub 2023 Jul 6.

Effectiveness of multiple disease-modifying therapies in relapsing-remitting multiple sclerosis: causal inference to emulate a multiarm randomised trial
Ibrahima Diouf, Charles B Malpas, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Francesco Patti, Vahid Shaygannejad, Serkan Ozakbas, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Patrizia Sola, Diana Ferraro, Pierre Grammond, Bassem Yamout, Ayse Altintas, Oliver Gerlach, Jeannette Lechner-Scott, Roberto Bergamaschi, Rana Karabudak, Gerardo Iuliano, Christopher McGuigan, Elisabetta Cartechini, Stella Hughes, Maria Jose Sa, Claudio Solaro, Ludwig Kappos, Suzanne Hodgkinson, Mark Slee, Franco Granella, Koen de Gans, Pamela A McCombe, Radek Ampapa, Anneke van der Walt, Helmut Butzkueven, José Luis Sánchez-Menoyo, Steve Vucic, Guy Laureys, Youssef Sidhom, Riadh Gouider, Tamara Castillo-Trivino, Orla Gray, Eduardo Aguera-Morales, Abdullah Al-Asmi, Cameron Shaw, Talal M Al-Harbi, Tunde Csepany, Angel P Sempere, Irene Treviño Frenk, Elizabeth A Stuart, Tomas Kalincik
J Neurol Neurosurg Psychiatry. 2023 Dec;94(12):1004-1011. doi: 10.1136/jnnp-2023-331499. Epub 2023 Jul 6.

The risk of secondary progressive multiple sclerosis is geographically determined but modifiable
Sifat Sharmin, Izanne Roos, Steve Simpson-Yap, Charles Malpas, Marina M Sánchez, Serkan Ozakbas, Dana Horakova, Eva K Havrdova, Francesco Patti, Raed Alroughani, Guillermo Izquierdo, Sara Eichau, Cavit Boz, Magd Zakaria, Marco Onofrj, Alessandra Lugaresi, Bianca Weinstock-Guttman, Alexandre Prat, Marc Girard, Pierre Duquette, Murat Terzi, Maria Pia Amato, Rana Karabudak, Francois Grand'Maison, Samia J Khoury, Pierre Grammond, Jeannette Lechner-Scott, Katherine Buzzard, Olga Skibina, Anneke van der Walt, Helmut Butzkueven, Recai Turkoglu, Ayse Altintas, Davide Maimone, Allan Kermode, Nevin Shalaby, Vincent V Pesch, Ernest Butler, Youssef Sidhom, Riadh Gouider, Saloua Mrabet, Oliver Gerlach, Aysun Soysal, Michael Barnett, Jens Kuhle, Stella Hughes, Maria J Sa, Suzanne Hodgkinson, Celia Oreja-Guevara, Radek Ampapa, Thor Petersen, Cristina Ramo-Tello, Daniele Spitaleri, Pamela McCombe, Bruce Taylor, Julie Prevost, Matteo Foschi, Mark Slee, Chris McGuigan, Guy Laureys, Liesbeth V Hijfte, Koen de Gans, Claudio Solaro, Jiwon Oh, Richard Macdonell, Eduardo Aguera-Morales, Bhim Singhal, Orla Gray, Justin Garber, Bart V Wijmeersch, Mihaela Simu, Tamara Castillo-Triviño, Jose L Sanchez-Menoyo, Dheeraj Khurana, Abdullah Al-Asmi, Talal Al-Harbi, Norma Deri, Yara Fragoso, Patrice H Lalive, L G F Sinnige, Cameron Shaw, Neil Shuey, Tunde Csepany, Angel P Sempere, Fraser Moore, Danny Decoo, Barbara Willekens, Claudio Gobbi, Jennifer Massey, Todd Hardy, John Parratt, Tomas Kalincik
Brain. 2023 Nov 2;146(11):4633-4644. doi: 10.1093/brain/awad218.

Rituximab vs Ocrelizumab in Relapsing-Remitting Multiple Sclerosis
Izanne Roos, Stella Hughes, Gavin McDonnell, Charles B Malpas, Sifat Sharmin, Cavit Boz, Raed Alroughani, Serkan Ozakbas, Katherine Buzzard, Olga Skibina, Anneke van der Walt, Helmut Butzkueven, Jeannette Lechner-Scott, Jens Kuhle, Murat Terzi, Guy Laureys, Liesbeth Van Hijfte, Nevin John, Pierre Grammond, Francois Grand'Maison, Aysun Soysal, Ana Voldsgaard Jensen, Peter Vestergaard Rasmussen, Kristina Bacher Svendsen, Ismael Barzinji, Helle Hvilsted Nielsen, Tobias Sejbæk, Sivagini Prakash, Morten Leif Munding Stilund, Arkadiusz Weglewski, Nadia Mubder Issa, Matthias Kant, Finn Sellebjerg, Orla Gray, Melinda Magyari, Tomas Kalincik, MSBase Study GroupDanish MS Registry Study Group
JAMA Neurol. 2023 Aug 1;80(8):789-797. doi: 10.1001/jamaneurol.2023.1625.

A plain language summary on the effectiveness of cladribine tablets compared with other oral treatments for multiple sclerosis: results from the MSBase registry
Tim Spelman, Serkan Ozakbas, Raed Alroughani, Murat Terzi, Suzanne Hodgkinson, Guy Laureys, Tomas Kalincik, Anneke Van Der Walt, Bassem Yamout, Jeannette Lechner-Scott, Aysun Soysal, Jens Kuhle, Jose Luis Sanchez-Menoyo, Yolanda Blanco Morgado, Daniele LA Spitaleri, Vincent van Pesch, Dana Horakova, Radek Ampapa, Francesco Patti, Richard Macdonell, Abdullah Al-Asmi, Oliver Gerlach, Jiwon Oh, Ayse Altintas, Namita Tundia, Schiffon L Wong, Helmut Butzkueven, MSBase Study Group
Neurodegener Dis Manag. 2023 Aug;13(4):215-221. doi: 10.2217/nmt-2023-0005. Epub 2023 Jun 7.

Comparison Between Dimethyl Fumarate, Fingolimod, and Ocrelizumab After Natalizumab Cessation
Chao Zhu, Tomas Kalincik, Dana Horakova, Zhen Zhou, Katherine Buzzard, Olga Skibina, Raed Alroughani, Guillermo Izquierdo, Sara Eichau, Jens Kuhle, Francesco Patti, Francois Grand'Maison, Suzanne Hodgkinson, Pierre Grammond, Jeannette Lechner-Scott, Ernest Butler, Alexandre Prat, Marc Girard, Pierre Duquette, Richard A L Macdonell, Bianca Weinstock-Guttman, Serkan Ozakbas, Mark Slee, Maria Jose Sa, Vincent Van Pesch, Michael Barnett, Bart Van Wijmeersch, Oliver Gerlach, Julie Prevost, Murat Terzi, Cavit Boz, Guy Laureys, Liesbeth Van Hijfte, Allan G Kermode, Justin Garber, Bassem Yamout, Samia J Khoury, Daniel Merlo, Mastura Monif, Vilija Jokubaitis, Anneke van der Walt, Helmut Butzkueven, MSBase Study Group
JAMA Neurol. 2023 Jul 1;80(7):739-748. doi: 10.1001/jamaneurol.2023.1542.

Modelling accessibility of adult neurology care in Australia, 2020-2034
Steve Simpson-Yap, Federico Frascoli, Lucinda Harrison, Charles Malpas, James Burrell, Nicholas Child, Lauren P Giles, Christian Lueck, Merrilee Needham, Benjamin Tsang, Tomas Kalincik
BMJ Neurol Open. 2023 Apr 27;5(1):e000407. doi: 10.1136/bmjno-2023-000407. eCollection 2023.

Cerebrospinal fluid neurofilament light predicts longitudinal diagnostic change in patients with psychiatric and neurodegenerative disorders
Matthew J Y Kang, Dhamidhu Eratne, Hannah Dobson, Charles B Malpas, Michael Keem, Courtney Lewis, Jasleen Grewal, Vivian Tsoukra, Christa Dang, Ramon Mocellin, Tomas Kalincik, Alexander F Santillo, Henrik Zetterberg, Kaj Blennow, Christiane Stehmann, Shiji Varghese, Qiao-Xin Li, Colin L Masters, Steven Collins, Samuel F Berkovic, Andrew Evans, Wendy Kelso, Sarah Farrand, Samantha M Loi, Mark Walterfang, Dennis Velakoulis
Acta Neuropsychiatr. 2024 Feb;36(1):17-28. doi: 10.1017/neu.2023.25. Epub 2023 Apr 28.

Disability accrual in primary and secondary progressive multiple sclerosis
Sam Harding-Forrester, Izanne Roos, Ai-Lan Nguyen, Charles B Malpas, Ibrahima Diouf, Nahid Moradi, Sifat Sharmin, Guillermo Izquierdo, Sara Eichau, Francesco Patti, Dana Horakova, Eva Kubala Havrdova, Alexandre Prat, Marc Girard, Pierre Duquette, Francois Grand'Maison, Marco Onofrj, Alessandra Lugaresi, Pierre Grammond, Serkan Ozakbas, Maria Pia Amato, Oliver Gerlach, Patrizia Sola, Diana Ferraro, Katherine Buzzard, Olga Skibina, Jeannette Lechner-Scott, Raed Alroughani, Cavit Boz, Vincent Van Pesch, Elisabetta Cartechini, Murat Terzi, Davide Maimone, Cristina Ramo-Tello, Bassem Yamout, Samia Joseph Khoury, Daniele La Spitaleri, Maria Jose Sa, Yolanda Blanco, Franco Granella, Mark Slee, Ernest Butler, Youssef Sidhom, Riadh Gouider, Roberto Bergamaschi, Rana Karabudak, Radek Ampapa, José Luis Sánchez-Menoyo, Julie Prevost, Tamara Castillo-Trivino, Pamela A McCombe, Richard Macdonell, Guy Laureys, Liesbeth Van Hijfte, Jiwon Oh, Ayse Altintas, Koen de Gans, Recai Turkoglu, Anneke van der Walt, Helmut Butzkueven, Steve Vucic, Michael Barnett, Edgardo Cristiano, Suzanne Hodgkinson, Gerardo Iuliano, Ludwig Kappos, Jens Kuhle, Vahid Shaygannejad, Aysun Soysal, Bianca Weinstock-Guttman, Bart Van Wijmeersch, Tomas Kalincik, MSBase investigators
J Neurol Neurosurg Psychiatry. 2023 Sep;94(9):707-717. doi: 10.1136/jnnp-2022-330726. Epub 2023 Apr 17.

Optimal sensor location and direction to accurately classify people with early-stage multiple sclerosis using gait stability
L Eduardo Cofré Lizama, Maya G Panisset, Liuhua Peng, Ying Tan, Tomas Kalincik, Mary P Galea
Gait Posture. 2023 May;102:39-42. doi: 10.1016/j.gaitpost.2023.02.009. Epub 2023 Feb 23.

Early non-disabling relapses are important predictors of disability accumulation in people with relapsing-remitting multiple sclerosis
Cyrus Daruwalla, Vahid Shaygannejad, Serkan Ozakbas, Eva Kubala Havrdova, Dana Horakova, Raed Alroughani, Cavit Boz, Francesco Patti, Marco Onofrj, Alessandra Lugaresi, Sara Eichau, Marc Girard, Alexandre Prat, Pierre Duquette, Bassem Yamout, Samia J Khoury, Seyed Aidin Sajedi, Recai Turkoglu, Ayse Altintas, Olga Skibina, Katherine Buzzard, Pierre Grammond, Rana Karabudak, Anneke van der Walt, Helmut Butzkueven, Davide Maimone, Jeannette Lechner-Scott, Aysun Soysal, Nevin John, Julie Prevost, Daniele Spitaleri, Cristina Ramo-Tello, Oliver Gerlach, Gerardo Iuliano, Matteo Foschi, Radek Ampapa, Vincent van Pesch, Michael Barnett, Nevin Shalaby, Marie D'hooghe, Jens Kuhle, Maria Jose Sa, Marzena Fabis-Pedrini, Allan Kermode, Saloua Mrabet, Riadh Gouider, Suzanne Hodgkinson, Guy Laureys, Liesbeth Van Hijfte, Richard Macdonell, Celia Oreja-Guevara, Edgardo Cristiano, Pamela McCombe, Jose Luis Sanchez-Menoyo, Bhim Singhal, Yolanda Blanco, Stella Hughes, Justin Garber, Claudio Solaro, Chris McGuigan, Bruce Taylor, Koen de Gans, Mario Habek, Abdullah Al-Asmi, Simu Mihaela, Tamara Castillo Triviño, Talal Al-Harbi, Juan Ignacio Rojas, Orla Gray, Dheeraj Khurana, Bart Van Wijmeersch, Nikolaos Grigoriadis, Jihad Inshasi, Jiwon Oh, Eduardo Aguera-Morales, Yara Fragoso, Fraser Moore, Cameron Shaw, Seyed Mohammad Baghbanian, Neil Shuey, Barbara Willekens, Todd A Hardy, Danny Decoo, Angel Perez Sempere, Deborah Field, Ray Wynford-Thomas, Nick G Cunniffe, Izanne Roos, Charles B Malpas, Alasdair J Coles, Tomas Kalincik, J William L Brown
Mult Scler. 2023 Jun;29(7):875-883. doi: 10.1177/13524585231151951. Epub 2023 Feb 27.

Seizure risk in multiple sclerosis patients treated with disease-modifying therapy: A systematic review and network meta-analysis
Yew Li Dang, Vivien Ty Yong, Sifat Sharmin, Piero Perucca, Tomas Kalincik
Mult Scler. 2023 May;29(6):657-667. doi: 10.1177/13524585231151400. Epub 2023 Feb 19.

Comparative effectiveness in multiple sclerosis: A methodological comparison
Izanne Roos, Ibrahima Diouf, Sifat Sharmin, Dana Horakova, Eva Kubala Havrdova, Francesco Patti, Vahid Shaygannejad, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Marc Girard, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Patrizia Sola, Diana Ferraro, Pierre Grammond, Recai Turkoglu, Katherine Buzzard, Olga Skibina, Bassem Yamou, Ayse Altintas, Oliver Gerlach, Vincent van Pesch, Yolanda Blanco, Davide Maimone, Jeannette Lechner-Scott, Roberto Bergamaschi, Rana Karabudak, Chris McGuigan, Elisabetta Cartechini, Michael Barnett, Stella Hughes, Maria José Sa, Claudio Solaro, Cristina Ramo-Tello, Suzanne Hodgkinson, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Franco Granella, Koen de Gans, Pamela McCombe, Radek Ampapa, Bart Van Wijmeersch, Anneke van der Walt, Helmut Butzkueven, Julie Prevost, Jose Luis Sanchez-Menoyo, Guy Laureys, Riadh Gouider, Tamara Castillo-Triviño, Orla Gray, Eduardo Aguera-Morales, Abdullah Al-Asmi, Cameron Shaw, Norma Deri, Talal Al-Harbi, Yara Fragoso, Tunde Csepany, Angel Perez Sempere, Irene Trevino-Frenk, Jan Schepel, Fraser Moore, Charles Malpas, Tomas Kalincik
Mult Scler. 2023 Mar;29(3):326-332. doi: 10.1177/13524585231151394. Epub 2023 Feb 19.

Switching to natalizumab or fingolimod in multiple sclerosis: Comparative effectiveness and effect of pre-switch disease activity
Tim Spelman, Dana Horakova, Serkan Ozakbas, Raed Alroughani, Marco Onofrj, Tomas Kalincik, Alexandre Prat, Murat Terzi, Pierre Grammond, Francesco Patti, Tunde Csepany, Cavit Boz, Jeannette Lechner-Scott, Franco Granella, Francois Grand'Maison, Anneke van der Walt, Chao Zhu, Helmut Butzkueven, MSBase Study Group
Mult Scler Relat Disord. 2023 Feb;70:104477. doi: 10.1016/j.msard.2022.104477. Epub 2022 Dec 23.

Variability of the response to immunotherapy among subgroups of patients with multiple sclerosis
Ibrahima Diouf, Charles B Malpas, Sifat Sharmin, Izanne Roos, Dana Horakova, Eva Kubala Havrdova, Francesco Patti, Vahid Shaygannejad, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Marc Girard, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Sherif Hamdy, Patrizia Sola, Diana Ferraro, Pierre Grammond, Recai Turkoglu, Katherine Buzzard, Olga Skibina, Bassem Yamout, Ayse Altintas, Oliver Gerlach, Vincent van Pesch, Yolanda Blanco, Davide Maimone, Jeannette Lechner-Scott, Roberto Bergamaschi, Rana Karabudak, Gerardo Iuliano, Chris McGuigan, Elisabetta Cartechini, Michael Barnett, Stella Hughes, Maria José Sa, Claudio Solaro, Ludwig Kappos, Cristina Ramo-Tello, Edgardo Cristiano, Suzanne Hodgkinson, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Mark Slee, Ernest Butler, Franco Granella, Koen de Gans, Pamela McCombe, Radek Ampapa, Bart Van Wijmeersch, Anneke van der Walt, Helmut Butzkueven, Julie Prevost, L G F Sinnige, Jose Luis Sanchez-Menoyo, Steve Vucic, Guy Laureys, Liesbeth Van Hijfte, Dheeraj Khurana, Richard Macdonell, Riadh Gouider, Tamara Castillo-Triviño, Orla Gray, Eduardo Aguera-Morales, Abdullah Al-Asmi, Cameron Shaw, Norma Deri, Talal Al-Harbi, Yara Fragoso, Tunde Csepany, Angel Perez Sempere, Irene Trevino-Frenk, Jan Schepel, Fraser Moore, Tomas Kalincik
Eur J Neurol. 2023 Apr;30(4):1014-1024. doi: 10.1111/ene.15706. Epub 2023 Feb 16.

Neuroimaging characteristics may aid in diagnosis, subtyping, and prognosis in autoimmune encephalitis
James Broadley, Robb Wesselingh, Paul Beech, Udaya Seneviratne, Chris Kyndt, Katherine Buzzard, Cassie Nesbitt, Wendyl D'Souza, Amy Brodtmann, Richard Macdonell, Tomas Kalincik, Terence J O'Brien, Helmut Butzkueven, Mastura Monif, Australian Autoimmune Encephalitis Consortium
Neurol Sci. 2023 Apr;44(4):1327-1340. doi: 10.1007/s10072-022-06523-9. Epub 2022 Dec 8.

External validation of a clinical prediction model in multiple sclerosis
Nahid Moradi, Sifat Sharmin, Charles B Malpas, Vahid Shaygannejad, Murat Terzi, Cavit Boz, Bassem Yamout, Samia J Khoury, Recai Turkoglu, Rana Karabudak, Nevin Shalaby, Aysun Soysal, Ayşe Altıntaş, Jihad Inshasi, Talal Al-Harbi, Raed Alroughani, Tomas Kalincik
Mult Scler. 2023 Feb;29(2):261-269. doi: 10.1177/13524585221136036. Epub 2022 Nov 30.

Not all roads lead to the immune system: the genetic basis of multiple sclerosis severity
Vilija G Jokubaitis, Maria Pia Campagna, Omar Ibrahim, Jim Stankovich, Pavlina Kleinova, Fuencisla Matesanz, Daniel Hui, Sara Eichau, Mark Slee, Jeannette Lechner-Scott, Rodney Lea, Trevor J Kilpatrick, Tomas Kalincik, Philip L De Jager, Ashley Beecham, Jacob L McCauley, Bruce V Taylor, Steve Vucic, Louise Laverick, Karolina Vodehnalova, Maria-Isabel García-Sanchéz, Antonio Alcina, Anneke van der Walt, Eva Kubala Havrdova, Guillermo Izquierdo, Nikolaos Patsopoulos, Dana Horakova, Helmut Butzkueven
Brain. 2023 Jun 1;146(6):2316-2331. doi: 10.1093/brain/awac449.

Comparative effectiveness of cladribine tablets versus other oral disease-modifying treatments for multiple sclerosis: Results from MSBase registry
Tim Spelman, Serkan Ozakbas, Raed Alroughani, Murat Terzi, Suzanne Hodgkinson, Guy Laureys, Tomas Kalincik, Anneke Van Der Walt, Bassem Yamout, Jeannette Lechner-Scott, Aysun Soysal, Jens Kuhle, Jose Luis Sanchez-Menoyo, Yolanda Blanco Morgado, Daniele LA Spitaleri, Vincent van Pesch, Dana Horakova, Radek Ampapa, Francesco Patti, Richard Macdonell, Abdullah Al-Asmi, Oliver Gerlach, Jiwon Oh, Ayse Altintas, Namita Tundia, Schiffon L Wong, Helmut Butzkueven
Mult Scler. 2023 Feb;29(2):221-235. doi: 10.1177/13524585221137502. Epub 2022 Nov 26.

Comparing switch to ocrelizumab, cladribine or natalizumab after fingolimod treatment cessation in multiple sclerosis
Chao Zhu, Zhen Zhou, Izanne Roos, Daniel Merlo, Tomas Kalincik, Serkan Ozakbas, Olga Skibina, Jens Kuhle, Suzanne Hodgkinson, Cavit Boz, Raed Alroughani, Jeannette Lechner-Scott, Michael Barnett, Guillermo Izquierdo, Alexandre Prat, Dana Horakova, Eva Kubala Havrdova, Richard Macdonell, Francesco Patti, Samia Joseph Khoury, Mark Slee, Rana Karabudak, Marco Onofrj, Vincent Van Pesch, Julie Prevost, Mastura Monif, Vilija Jokubaitis, Anneke van der Walt, Helmut Butzkueven, MSBase Study Group
J Neurol Neurosurg Psychiatry. 2022 Dec;93(12):1330-1337. doi: 10.1136/jnnp-2022-330104. Epub 2022 Oct 19.

Early predictors of disability in paediatric multiple sclerosis: evidence from a multi-national registry
Sifat Sharmin, Charles B Malpas, Izanne Roos, Ibrahima Diouf, Raed Alroughani, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Dana Horakova, Eva K Havrdova, Francesco Patti, Murat Terzi, Cavit Boz, Bassem Yamout, Samia J Khoury, Marco Onofrj, Alessandra Lugaresi, Ayse Altintas, Alexandre Prat, Marc Girard, Pierre Duquette, Maria José Sá, Daniele La Spitaleri, Youssef Sidhom, Riadh Gouider, Saloua Mrabet, Aysun Soysal, Recai Turkoglu, Maria Pia Amato, Yara D Fragoso, Tomas Kalincik
J Neurol Neurosurg Psychiatry. 2022 Sep 30:jnnp-2022-329713. doi: 10.1136/jnnp-2022-329713. Online ahead of print.

Heterogeneity on long-term disability trajectories in patients with secondary progressive MS: a latent class analysis from Big MS Data network
Alessio Signori, Johannes Lorscheider, Sandra Vukusic, Maria Trojano, Pietro Iaffaldano, Jan Hillert, Robert Hyde, Fabio Pellegrini, Melinda Magyari, Nils Koch-Henriksen, Per Soelberg Sørensen, Tim Spelman, Anneke van der Walt, Dana Horakova, Eva Havrdova, Marc Girard, Sara Eichau, Francois Grand'Maison, Oliver Gerlach, Murat Terzi, Serkan Ozakbas, Olga Skibina, Vincent Van Pesch, Maria Jose Sa, Julie Prevost, Raed Alroughani, Pamela A McCombe, Riadh Gouider, Saloua Mrabet, Tamara Castillo-Trivino, Chao Zhu, Koen de Gans, José Luis Sánchez-Menoyo, Bassem Yamout, Samia Khoury, Maria Pia Sormani, Tomas Kalincik, Helmut Butzkueven, Big MS Data Network
J Neurol Neurosurg Psychiatry. 2023 Jan;94(1):23-30. doi: 10.1136/jnnp-2022-329987. Epub 2022 Sep 28.

Using the EQ-5D-5L to investigate quality-of-life impacts of disease-modifying therapy policies for people with multiple sclerosis (MS) in New Zealand
Suzi Claflin, Julie A Campbell, Richard Norman, Deborah F Mason, Tomas Kalincik, Steve Simpson-Yap, Helmut Butzkueven, William M Carroll, Andrew J Palmer, C Leigh Blizzard, Ingrid van der Mei, Glen J Henson, Bruce V Taylor
Eur J Health Econ. 2023 Aug;24(6):939-950. doi: 10.1007/s10198-022-01518-x. Epub 2022 Sep 23.

Efficacy of botulinum toxin type a in the targeted treatment of sleep bruxism: a double-blind, randomised, placebo-controlled, cross-over study
Belinda Cruse, Thanuja Dharmadasa, Elise White, Callum Hollis, Andrew Evans, Sifat Sharmin, Tomas Kalincik, Lynette Kiers
BMJ Neurol Open. 2022 Sep 5;4(2):e000328. doi: 10.1136/bmjno-2022-000328. eCollection 2022.

Updated Results of the COVID-19 in MS Global Data Sharing Initiative: Anti-CD20 and Other Risk Factors Associated With COVID-19 Severity
Steve Simpson-Yap, Ashkan Pirmani, Tomas Kalincik, Edward De Brouwer, Lotte Geys, Tina Parciak, Anne Helme, Nick Rijke, Jan A Hillert, Yves Moreau, Gilles Edan, Sifat Sharmin, Tim Spelman, Robert McBurney, Hollie Schmidt, Arnfin B Bergmann, Stefan Braune, Alexander Stahmann, Rod M Middleton, Amber Salter, Bruce Bebo, Anneke Van der Walt, Helmut Butzkueven, Serkan Ozakbas, Cavit Boz, Rana Karabudak, Raed Alroughani, Juan I Rojas, Ingrid A van der Mei, Guilherme Sciascia do Olival, Melinda Magyari, Ricardo N Alonso, Richard S Nicholas, Anibal S Chertcoff, Ana Zabalza de Torres, Georgina Arrambide, Nupur Nag, Annabel Descamps, Lars Costers, Ruth Dobson, Aleisha Miller, Paulo Rodrigues, Vesna Prčkovska, Giancarlo Comi, Liesbet M Peeters
Neurol Neuroimmunol Neuroinflamm. 2022 Aug 29;9(6):e200021. doi: 10.1212/NXI.0000000000200021. Print 2022 Nov.

Disease Reactivation After Cessation of Disease-Modifying Therapy in Patients With Relapsing-Remitting Multiple Sclerosis
Izanne Roos, Charles Malpas, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Kubala Havrdova, Marc Debouverie, Francesco Patti, Jerome De Seze, Guillermo Izquierdo, Sara Eichau, Gilles Edan, Alexandre Prat, Marc Girard, Serkan Ozakbas, Pierre Grammond, Helene Zephir, Jonathan Ciron, Elisabeth Maillart, Thibault Moreau, Maria Pia Amato, Pierre Labauge, Raed Alroughani, Katherine Buzzard, Olga Skibina, Murat Terzi, David Axel Laplaud, Eric Berger, Francois Grand'Maison, Christine Lebrun-Frenay, Elisabetta Cartechini, Cavit Boz, Jeannette Lechner-Scott, Pierre Clavelou, Bruno Stankoff, Julie Prevost, Ludwig Kappos, Jean Pelletier, Vahid Shaygannejad, Bassem I Yamout, Samia J Khoury, Oliver Gerlach, Daniele L A Spitaleri, Vincent Van Pesch, Olivier Gout, Recai Turkoglu, Olivier Heinzlef, Eric Thouvenot, Pamela Ann McCombe, Aysun Soysal, Bertrand Bourre, Mark Slee, Tamara Castillo-Trivino, Serge Bakchine, Radek Ampapa, Ernest Gerard Butler, Abir Wahab, Richard A Macdonell, Eduardo Aguera-Morales, Philippe Cabre, Nasr Haifa Ben, Anneke Van der Walt, Guy Laureys, Liesbeth Van Hijfte, Cristina M Ramo-Tello, Nicolas Maubeuge, Suzanne Hodgkinson, José Luis Sánchez-Menoyo, Michael H Barnett, Celine Labeyrie, Steve Vucic, Youssef Sidhom, Riadh Gouider, Tunde Csepany, Javier Sotoca, Koen de Gans, Abdullah Al-Asmi, Yara Dadalti Fragoso, Sandra Vukusic, Helmut Butzkueven, Tomas Kalincik, MSBase and OFSEP
Neurology. 2022 Oct 25;99(17):e1926-e1944. doi: 10.1212/WNL.0000000000201029. Epub 2022 Aug 17.

Severity of COVID19 infection among patients with multiple sclerosis treated with interferon-β
Steve Simpson-Yap, Ashkan Pirmani, Edward De Brouwer, Liesbet M Peeters, Lotte Geys, Tina Parciak, Anne Helme, Jan Hillert, Yves Moreau, Gilles Edan, Tim Spelman, Sifat Sharmin, Robert McBurney, Hollie Schmidt, Arnfin Bergmann, Stefan Braune, Alexander Stahmann, Rodden Middleton, Amber Salter, Bruce Bebo, Anneke van der Walt, Helmut Butzkueven, Serkan Ozakbas, Rana Karabudak, Cavit Boz, Raed Alroughani, Juan I Rojas, Ingrid van der Mei, Guilherme Sciascia do Olival, Melinda Magyari, Ricardo Alonso, Richard Nicholas, Anibal Chertcoff, Ana Zabalza, Georgina Arrambide, Nupur Nag, Annabel Descamps, Lars Costers, Ruth Dobson, Aleisha Miller, Paulo Rodrigues, Vesna Prčkovska, Giancarlo Comi, Tomas Kalincik
Mult Scler Relat Disord. 2022 Oct;66:104072. doi: 10.1016/j.msard.2022.104072. Epub 2022 Jul 25.

Superior effects of natalizumab versus other DMTs on patient-reported outcomes in people with multiple sclerosis
Jing Chen, Ibrahima Diouf, Bruce V Taylor, Tomas Kalincik, Ingrid van der Mei
J Neurol Neurosurg Psychiatry. 2022 Jul 28:jnnp-2022-329223. doi: 10.1136/jnnp-2022-329223. Online ahead of print.

Prediction of relapse activity when switching to cladribine for multiple sclerosis
Michael Zhong, Anneke van der Walt, Mastura Monif, Suzanne Hodgkinson, Sara Eichau, Tomas Kalincik, Jeannette Lechner-Scott, Katherine Buzzard, Olga Skibina, Vincent Van Pesch, Ernest Butler, Julie Prevost, Marc Girard, Jiwon Oh, Helmut Butzkueven, Vilija Jokubaitis
Mult Scler. 2023 Jan;29(1):119-129. doi: 10.1177/13524585221111677. Epub 2022 Jul 27.

Interrogating large multiple sclerosis registries and databases: what information can be gained?
Maria Trojano, Tomas Kalincik, Pietro Iaffaldano, Maria P Amato
Curr Opin Neurol. 2022 Jun 1;35(3):271-277. doi: 10.1097/WCO.0000000000001057.

Impact of telehealth on health care in a multiple sclerosis outpatient clinic during the COVID-19 pandemic
Vivien Li, Izanne Roos, Mastura Monif, Charles Malpas, Stefanie Roberts, Mark Marriott, Katherine Buzzard, Ai-Lan Nguyen, Nabil Seery, Lisa Taylor, Tomas Kalincik, Trevor Kilpatrick
Mult Scler Relat Disord. 2022 Jul;63:103913. doi: 10.1016/j.msard.2022.103913. Epub 2022 May 27.

Impact of methodological choices in comparative effectiveness studies: application in natalizumab versus fingolimod comparison among patients with multiple sclerosis
M Lefort, S Sharmin, J B Andersen, S Vukusic, R Casey, M Debouverie, G Edan, J Ciron, A Ruet, J De Sèze, E Maillart, H Zephir, P Labauge, G Defer, C Lebrun-Frenay, T Moreau, E Berger, P Clavelou, J Pelletier, B Stankoff, O Gout, E Thouvenot, O Heinzlef, A Al-Khedr, B Bourre, O Casez, P Cabre, A Montcuquet, A Wahab, J P Camdessanché, A Maurousset, H Ben Nasr, K Hankiewicz, C Pottier, N Maubeuge, D Dimitri-Boulos, C Nifle, D A Laplaud, D Horakova, E K Havrdova, R Alroughani, G Izquierdo, S Eichau, S Ozakbas, F Patti, M Onofrj, A Lugaresi, M Terzi, P Grammond, F Grand'Maison, B Yamout, A Prat, M Girard, P Duquette, C Boz, M Trojano, P McCombe, M Slee, J Lechner-Scott, R Turkoglu, P Sola, D Ferraro, F Granella, V Shaygannejad, J Prevost, D Maimone, O Skibina, K Buzzard, A Van der Walt, R Karabudak, B Van Wijmeersch, T Csepany, D Spitaleri, S Vucic, N Koch-Henriksen, F Sellebjerg, P S Soerensen, C C Hilt Christensen, P V Rasmussen, M B Jensen, J L Frederiksen, S Bramow, H K Mathiesen, K I Schreiber, H Butzkueven, M Magyari, T Kalincik, E Leray
BMC Med Res Methodol. 2022 May 30;22(1):155. doi: 10.1186/s12874-022-01623-8.

Confirmed disability progression as a marker of permanent disability in multiple sclerosis
Sifat Sharmin, Francesca Bovis, Charles Malpas, Dana Horakova, Eva Kubala Havrdova, Guillermo Izquierdo, Sara Eichau, Maria Trojano, Alexandre Prat, Marc Girard, Pierre Duquette, Marco Onofrj, Alessandra Lugaresi, Francois Grand'Maison, Pierre Grammond, Patrizia Sola, Diana Ferraro, Murat Terzi, Oliver Gerlach, Raed Alroughani, Cavit Boz, Vahid Shaygannejad, Vincent van Pesch, Elisabetta Cartechini, Ludwig Kappos, Jeannette Lechner-Scott, Roberto Bergamaschi, Recai Turkoglu, Claudio Solaro, Gerardo Iuliano, Franco Granella, Bart Van Wijmeersch, Daniele Spitaleri, Mark Slee, Pamela McCombe, Julie Prevost, Radek Ampapa, Serkan Ozakbas, Jose Luis Sanchez-Menoyo, Aysun Soysal, Steve Vucic, Thor Petersen, Koen de Gans, Ernest Butler, Suzanne Hodgkinson, Youssef Sidhom, Riadh Gouider, Edgardo Cristiano, Tamara Castillo-Triviño, Maria Laura Saladino, Michael Barnett, Fraser Moore, Csilla Rozsa, Bassem Yamout, Olga Skibina, Anneke van der Walt, Katherine Buzzard, Orla Gray, Stella Hughes, Angel Perez Sempere, Bhim Singhal, Yara Fragoso, Cameron Shaw, Allan Kermode, Bruce Taylor, Magdolna Simo, Neil Shuey, Talal Al-Harbi, Richard Macdonell, Jose Andres Dominguez, Tunde Csepany, Carmen Adella Sirbu, Maria Pia Sormani, Helmut Butzkueven, Tomas Kalincik
Eur J Neurol. 2022 Aug;29(8):2321-2334. doi: 10.1111/ene.15406. Epub 2022 Jun 9.

Neuroimaging findings in immune effector cell associated neurotoxicity syndrome after chimeric antigen receptor T-cell therapy
Adam H Lapidus, Mary Ann Anderson, Simon J Harrison, Michael Dickinson, Tomas Kalincik, Arian Lasocki
Leuk Lymphoma. 2022 Oct;63(10):2364-2374. doi: 10.1080/10428194.2022.2074990. Epub 2022 May 14.

A comparison of macular ganglion cell and retinal nerve fibre layer optical coherence tomographic parameters as predictors of visual outcomes of surgery for pituitary tumours
Joos Meyer, Ibrahima Diouf, James King, Kate Drummond, Stan Stylli, Andrew Kaye, Tomas Kalincik, Helen Danesh-Meyer, R C Andrew Symons
Pituitary. 2022 Aug;25(4):563-572. doi: 10.1007/s11102-022-01228-w. Epub 2022 May 13.

Association of Latitude and Exposure to Ultraviolet B Radiation With Severity of Multiple Sclerosis: An International Registry Study
Marianna Vitkova, Ibrahima Diouf, Charles Malpas, Dana Horakova, Eva Kubala Havrdova, Francesco Patti, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Vahid Shaygannejad, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Catherine Larochelle, Marc Girard, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Patrizia Sola, Diana Ferraro, Pierre Grammond, Helmut Butzkueven, Katherine Buzzard, Olga Skibina, Bassem I Yamout, Rana Karabudak, Oliver Gerlach, Jeannette Lechner-Scott, Davide Maimone, Roberto Bergamaschi, Vincent Van Pesch, Gerardo Iuliano, Elisabetta Cartechini, Maria José Sà, Radek Ampapa, Michael Barnett, Stella E Hughes, Cristina M Ramo-Tello, Suzanne Hodgkinson, Daniele L A Spitaleri, Thor Petersen, Ernest Gerard Butler, Mark Slee, Chris McGuigan, Pamela Ann McCombe, Franco Granella, Edgardo Cristiano, Julie Prevost, Bruce V Taylor, Josã Luis Sãnchez-Menoyo, Guy Laureys, Liesbeth Van Hijfte, Steve Vucic, Richard A Macdonell, Orla Gray, Javier Olascoaga, Norma Deri, Yara Dadalti Fragoso, Cameron Shaw, Tomas Kalincik, MSBase Study Group
Neurology. 2022 Jun 14;98(24):e2401-e2412. doi: 10.1212/WNL.0000000000200545. Epub 2022 Apr 11.

Multiple Sclerosis Severity Score (MSSS) improves the accuracy of individualized prediction in MS
Tomas Kalincik, Ilya Kister, Tamar E Bacon, Charles B Malpas, Sifat Sharmin, Dana Horakova, Eva Kubala-Havrdova, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Serkan Ozakbas, Marco Onofrj, Alessandra Lugaresi, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Patrizia Sola, Diana Ferraro, Raed Alroughani, Murat Terzi, Cavit Boz, Francois Grand'Maison, Roberto Bergamaschi, Oliver Gerlach, Maria J Sa, Ludwig Kappos, Elisabetta Cartechini, Jeannette Lechner-Scott, Vincent van Pesch, Vahid Shaygannejad, Franco Granella, Daniele Spitaleri, Gerardo Iuliano, Davide Maimone, Julie Prevost, Aysun Soysal, Recai Turkoglu, Radek Ampapa, Helmut Butzkueven, Gary Cutter, for MSBase Study Group
Mult Scler. 2022 Oct;28(11):1752-1761. doi: 10.1177/13524585221084577. Epub 2022 Apr 3.

Multiple Sclerosis Relapses Following Cessation of Fingolimod
Charles B Malpas, Izanne Roos, Sifat Sharmin, Katherine Buzzard, Olga Skibina, Helmut Butzkueven, Ludwig Kappos, Francesco Patti, Raed Alroughani, Dana Horakova, Eva Kubala Havrdova, Guillermo Izquierdo, Sara Eichau, Suzanne Hodgkinson, Pierre Grammond, Jeannette Lechner-Scott, Tomas Kalincik, MSBase Study Group
Clin Drug Investig. 2022 Apr;42(4):355-364. doi: 10.1007/s40261-022-01129-7. Epub 2022 Mar 18.

The dynamics of relapses during treatment switch in relapsing-remitting multiple sclerosis
Federico Frascoli, Izanne Roos, Charles B Malpas, Tomas Kalincik
J Theor Biol. 2022 May 21;541:111091. doi: 10.1016/j.jtbi.2022.111091. Epub 2022 Mar 11.

Diagnosis, differential diagnosis and misdiagnosis of Susac syndrome
James D Triplett, Jessica Qiu, Billy O'Brien, Sumana Gopinath, Benjamin Trewin, Penelope J Spring, Mohamed Shaffi, Jerome Ip, Fiona Chan, Luke Chen, Ian Wilson, Claire Muller, Heidi N Beadnall, Mike Boggild, Anneke Van der Walt, Richard Roxburgh, Nabil Seery, Tomas Kalincik, Michael H Barnett, John D E Parratt, Stephen W Reddel, Benjamin Tsang, Todd A Hardy
Eur J Neurol. 2022 Jun;29(6):1771-1781. doi: 10.1111/ene.15317. Epub 2022 Mar 25.

Factors associated with treatment escalation among MS specialists and general neurologists: Results from an International cojoint study
G Saposnik, S Andhavarapu, Ó Fernández, H J Kim, H Wiendl, M Foss, F Zuo, E K Havrdová, E Celius, F Caceres, M Magyari, R Bermel, A Costa, M Terzaghi, T Kalincik, V Popescu, M P Amato, X Montalban, J Oh
Mult Scler Relat Disord. 2022 Feb;58:103404. doi: 10.1016/j.msard.2021.103404. Epub 2021 Nov 16.

Subjective versus objective performance in people with multiple sclerosis using the MSReactor computerised cognitive tests
Daniel Merlo, Tomas Kalincik, Chao Zhu, Melissa Gresle, Jeannette Lechner-Scott, Trevor Kilpatrick, Michael Barnett, Bruce Taylor, Katherine Buzzard, David Darby, Helmut Butzkueven, Anneke van der Walt
Mult Scler Relat Disord. 2022 Feb;58:103393. doi: 10.1016/j.msard.2021.103393. Epub 2021 Nov 10.

Plasma neurofilament light chain protein is not increased in treatment-resistant schizophrenia and first-degree relatives
Dhamidhu Eratne, Shorena Janelidze, Charles B Malpas, Samantha Loi, Mark Walterfang, Antonia Merritt, Ibrahima Diouf, Kaj Blennow, Henrik Zetterberg, Brandon Cilia, Cassandra Wannan, Chad Bousman, Ian Everall, Andrew Zalesky, Mahesh Jayaram, Naveen Thomas, Samuel F Berkovic, Oskar Hansson, Dennis Velakoulis, Christos Pantelis, Alexander Santillo, MiND Study Group
Aust N Z J Psychiatry. 2022 Oct;56(10):1295-1305. doi: 10.1177/00048674211058684. Epub 2021 Nov 17.

Effect of desire for pregnancy on decisions to escalate treatment in multiple sclerosis care: Differences between MS specialists and non-MS specialists
Gustavo Saposnik, Sanketh Andhavarapu, Óscar Fernández, Ho Jin Kim, Heinz Wiendl, Mona Foss, Fei Zuo, Eva Kubala Havrdová, Elisabeth Gulowsen Celius, Fernando Caceres, Melinda Magyari, Robert Bermel, Andreia Costa, Maria Terzaghi, Tomas Kalincik, Veronica Popescu, Maria Pia Amato, Xavier Montalban, Jiwon Oh
Mult Scler Relat Disord. 2022 Jan;57:103389. doi: 10.1016/j.msard.2021.103389. Epub 2021 Nov 13.

Comparative Effectiveness and Cost-Effectiveness of Natalizumab and Fingolimod in Patients with Inadequate Response to Disease-Modifying Therapies in Relapsing-Remitting Multiple Sclerosis in the United Kingdom
Timothy Spelman, William L Herring, Yuanhui Zhang, Michael Tempest, Isobel Pearson, Ulrich Freudensprung, Carlos Acosta, Thibaut Dort, Robert Hyde, Eva Havrdova, Dana Horakova, Maria Trojano, Giovanna De Luca, Alessandra Lugaresi, Guillermo Izquierdo, Pierre Grammond, Pierre Duquette, Raed Alroughani, Eugenio Pucci, Franco Granella, Jeannette Lechner-Scott, Patrizia Sola, Diana Ferraro, Francois Grand'Maison, Murat Terzi, Csilla Rozsa, Cavit Boz, Raymond Hupperts, Vincent Van Pesch, Celia Oreja-Guevara, Anneke van der Walt, Vilija G Jokubaitis, Tomas Kalincik, Helmut Butzkueven, MSBase Investigators
Pharmacoeconomics. 2022 Mar;40(3):323-339. doi: 10.1007/s40273-021-01106-6. Epub 2021 Dec 18.

Corrigendum to Longitudinal machine learning modeling of MS patient trajectories improves predictions of disability progression: [Computer Methods and Programs in Biomedicine, Volume 208, (September 2021) 106180]
Edward De Brouwer, Thijs Becker, Yves Moreau, Eva Kubala Havrdova, Maria Trojano, Sara Eichau, Serkan Ozakbas, Marco Onofrj, Pierre Grammond, Jens Kuhle, Ludwig Kappos, Patrizia Sola, Elisabetta Cartechini, Jeannette Lechner-Scott, Raed Alroughani, Oliver Gerlach, Tomas Kalincik, Franco Granella, Francois Grand'Maison, Roberto Bergamaschi, Maria José Sá, Bart Van Wijmeersch, Aysun Soysal, Jose Luis Sanchez-Menoyo, Claudio Solaro, Cavit Boz, Gerardo Iuliano, Katherine Buzzard, Eduardo Aguera-Morales, Murat Terzi, Tamara Castillo Trivio, Daniele Spitaleri, Vincent Van Pesch, Vahid Shaygannejad, Fraser Moore, Celia Oreja-Guevara, Davide Maimone, Riadh Gouider, Tunde Csepany, Cristina Ramo-Tello, Liesbet Peeters
Comput Methods Programs Biomed. 2022 Jan;213:106479. doi: 10.1016/j.cmpb.2021.106479. Epub 2021 Nov 5.

High BMI in Youths as a Modifiable Risk Factor for Multiple Sclerosis: Weighing Up the Evidence
Tomas Kalincik, Helen Tremlett, Alberto Ascherio
Neurology. 2021 Dec 7;97(23):1057-1058. doi: 10.1212/WNL.0000000000012966. Epub 2021 Oct 25.

Efficacy of Cladribine Tablets as a Treatment for People With Multiple Sclerosis: Protocol for the CLOBAS Study (Cladribine, a Multicenter, Long-term Efficacy and Biomarker Australian Study)
Vicki E Maltby, Rodney A Lea, Mastura Monif, Marzena J Fabis-Pedrini, Katherine Buzzard, Tomas Kalincik, Allan G Kermode, Bruce Taylor, Suzanne Hodgkinson, Pamela McCombe, Helmut Butzkueven, Michael Barnett, Jeannette Lechner-Scott
JMIR Res Protoc. 2021 Oct 19;10(10):e24969. doi: 10.2196/24969.

Prediction of multiple sclerosis outcomes when switching to ocrelizumab
Michael Zhong, Anneke van der Walt, Jim Stankovich, Tomas Kalincik, Katherine Buzzard, Olga Skibina, Cavit Boz, Suzanne Hodgkinson, Mark Slee, Jeannette Lechner-Scott, Richard Macdonell, Julie Prevost, Jens Kuhle, Guy Laureys, Liesbeth Van Hijfte, Raed Alroughani, Allan G Kermode, Ernest Butler, Michael Barnett, Sara Eichau, Vincent van Pesch, Pierre Grammond, Pamela McCombe, Rana Karabudak, Pierre Duquette, Marc Girard, Bruce Taylor, Wei Yeh, Mastura Monif, Melissa Gresle, Helmut Butzkueven, Vilija G Jokubaitis
Mult Scler. 2022 May;28(6):958-969. doi: 10.1177/13524585211049986. Epub 2021 Oct 8.

Measurement of neurofilaments improves stratification of future disease activity in early multiple sclerosis
Tomas Uher, Eva Kubala Havrdova, Pascal Benkert, Niels Bergsland, Jan Krasensky, Barbora Srpova, Michael Dwyer, Michaela Tyblova, Stephanie Meier, Manuela Vaneckova, Dana Horakova, Robert Zivadinov, David Leppert, Tomas Kalincik, Jens Kuhle
Mult Scler. 2021 Nov;27(13):2001-2013. doi: 10.1177/13524585211047977. Epub 2021 Oct 6.

Associations of Disease-Modifying Therapies With COVID-19 Severity in Multiple Sclerosis
Steve Simpson-Yap, Edward De Brouwer, Tomas Kalincik, Nick Rijke, Jan A Hillert, Clare Walton, Gilles Edan, Yves Moreau, Tim Spelman, Lotte Geys, Tina Parciak, Clement Gautrais, Nikola Lazovski, Ashkan Pirmani, Amin Ardeshirdavanai, Lars Forsberg, Anna Glaser, Robert McBurney, Hollie Schmidt, Arnfin B Bergmann, Stefan Braune, Alexander Stahmann, Rodden Middleton, Amber Salter, Robert J Fox, Anneke van der Walt, Helmut Butzkueven, Raed Alroughani, Serkan Ozakbas, Juan I Rojas, Ingrid van der Mei, Nupur Nag, Rumen Ivanov, Guilherme Sciascia do Olival, Alice Estavo Dias, Melinda Magyari, Doralina Brum, Maria Fernanda Mendes, Ricardo N Alonso, Richard S Nicholas, Johana Bauer, Aníbal Sebastián Chertcoff, Anna Zabalza, Georgina Arrambide, Alexander Fidao, Giancarlo Comi, Liesbet Peeters
Neurology. 2021 Nov 9;97(19):e1870-e1885. doi: 10.1212/WNL.0000000000012753. Epub 2021 Oct 5.

Association Between Cognitive Trajectories and Disability Progression in Patients With Relapsing-Remitting Multiple Sclerosis
Daniel Merlo, Jim Stankovich, Claire Bai, Tomas Kalincik, Chao Zhu, Melissa Gresle, Jeannette Lechner-Scott, Trevor Kilpatrick, Michael Barnett, Bruce Taylor, David Darby, Helmut Butzkueven, Anneke Van der Walt
Neurology. 2021 Nov 16;97(20):e2020-e2031. doi: 10.1212/WNL.0000000000012850. Epub 2021 Sep 23.

Long-term outcomes in patients presenting with optic neuritis: Analyses of the MSBase registry
Rachel Kenney, Mengling Liu, Sachi Patil, Raed Alroughani, Radek Ampapa, Roberto Bergamaschi, Cavit Boz, Helmut Butzkueven, Jose Cabrera Gomez, Elisabetta Cartechini, Sara Eichau Madueño, Diana Ferraro, Francois Grand-Maison, Franco Granella, Dana Horakova, Guillermo Izquierdo Ayuso, Tomas Kalincik, Jana Lizrova Preiningerova, Alessandra Lugaresi, Marco Onofrj, Serkan Ozakbas, Francesco Patti, Patrizia Sola, Aysun Soysal, Daniele Litterio A Spitaleri, Murat Terzi, Recai Turkoglu, Vincent van Pesch, Shiv Saidha, Lorna E Thorpe, Steven L Galetta, Laura J Balcer, Ilya Kister, Tim Spelman, MSBase Study Group
J Neurol Sci. 2021 Nov 15;430:118067. doi: 10.1016/j.jns.2021.118067. Epub 2021 Sep 3.

Natalizumab Versus Fingolimod in Patients with Relapsing-Remitting Multiple Sclerosis: A Subgroup Analysis From Three International Cohorts
Sifat Sharmin, Mathilde Lefort, Johanna Balslev Andersen, Emmanuelle Leray, Dana Horakova, Eva Kubala Havrdova, Raed Alroughani, Guillermo Izquierdo, Serkan Ozakbas, Francesco Patti, Marco Onofrj, Alessandra Lugaresi, Murat Terzi, Pierre Grammond, Francois Grand'Maison, Bassem Yamout, Alexandre Prat, Marc Girard, Pierre Duquette, Cavit Boz, Maria Trojano, Pamela McCombe, Mark Slee, Jeannette Lechner-Scott, Recai Turkoglu, Patrizia Sola, Diana Ferraro, Franco Granella, Julie Prevost, Davide Maimone, Olga Skibina, Katherine Buzzard, Anneke Van der Walt, Bart Van Wijmeersch, Tunde Csepany, Daniele Spitaleri, Steve Vucic, Romain Casey, Marc Debouverie, Gilles Edan, Jonathan Ciron, Aurélie Ruet, Jérôme De Sèze, Elisabeth Maillart, Hélène Zephir, Pierre Labauge, Gilles Defer, Christine Lebrun-Frénay, Thibault Moreau, Eric Berger, Pierre Clavelou, Jean Pelletier, Bruno Stankoff, Olivier Gout, Eric Thouvenot, Olivier Heinzlef, Abullatif Al-Khedr, Bertrand Bourre, Olivier Casez, Philippe Cabre, Alexis Montcuquet, Abir Wahab, Jean-Philippe Camdessanché, Aude Maurousset, Ivania Patry, Karolina Hankiewicz, Corinne Pottier, Nicolas Maubeuge, Céline Labeyrie, Chantal Nifle, David Laplaud, Niels Koch-Henriksen, Finn Thorup Sellebjerg, Per Soelberg Soerensen, Claudia Christina Pfleger, Peter Vestergaard Rasmussen, Michael Broksgaard Jensen, Jette Lautrup Frederiksen, Stephan Bramow, Henrik Kahr Mathiesen, Karen Ingrid Schreiber, Melinda Magyari, Sandra Vukusic, Helmut Butzkueven, Tomas Kalincik, Danish Multiple Sclerosis Registry, OFSEP and the MSBase investigators
CNS Drugs. 2021 Nov;35(11):1217-1232. doi: 10.1007/s40263-021-00860-7. Epub 2021 Sep 18.

Brain atrophy and lesion burden are associated with disability progression in a multiple sclerosis real-world dataset using only T2-FLAIR: The NeuroSTREAM MSBase study
Michael Barnett, Niels Bergsland, Bianca Weinstock-Guttman, Helmut Butzkueven, Tomas Kalincik, Patricia Desmond, Frank Gaillard, Vincent van Pesch, Serkan Ozakbas, Juan Ignacio Rojas, Cavit Boz, Ayse Altintas, Chenyu Wang, Michael G Dwyer, Suzie Yang, Dejan Jakimovski, Kain Kyle, Deepa P Ramasamy, Robert Zivadinov
Neuroimage Clin. 2021;32:102802. doi: 10.1016/j.nicl.2021.102802. Epub 2021 Aug 24.

The effect of national disease-modifying therapy subsidy policy on long-term disability outcomes in people with multiple sclerosis
Suzi B Claflin, Julie A Campbell, Deborah F Mason, Tomas Kalincik, Steve Simpson-Yap, Richard Norman, Helmut Butzkueven, William M Carroll, Andrew J Palmer, C Leigh Blizzard, Ingrid van der Mei, Bruce V Taylor
Mult Scler. 2022 Apr;28(5):831-841. doi: 10.1177/13524585211035948. Epub 2021 Aug 13.

Effects of High- and Low-Efficacy Therapy in Secondary Progressive Multiple Sclerosis
Izanne Roos, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Havrdova, Guillermo Izquierdo, Sara Eichau Madueño, Francesco Patti, Gilles Edan, Marc Debouverie, Jean Pelletier, Serkan Ozakbas, Maria Pia Amato, Pierre Clavelou, Pierre Grammond, Cavit Boz, Katherine Buzzard, Olga Skibina, Jonathan Ciron, Oliver Gerlach, Francois Grand'Maison, Jeannette Lechner-Scott, Charles Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik, MSBase and OFSEP Study Groups
Neurology. 2021 Aug 31;97(9):e869-e880. doi: 10.1212/WNL.0000000000012354. Epub 2021 Jun 30.

Utilization of Multiple Sclerosis Therapies in the Middle East Over a Decade: 2009-2018
Nahid Moradi, Sifat Sharmin, Charles Malpas, Serkan Ozakbas, Vahid Shaygannejad, Murat Terzi, Cavit Boz, Bassem Yamout, Recai Turkoglu, Rana Karabudak, Sherif Hamdy, Aysun Soysal, Ayşe Altıntaş, Jihad Inshasi, Talal Al-Harbi, Raed Alroughani, Tomas Kalincik, MSBase Study Group
CNS Drugs. 2021 Oct;35(10):1097-1106. doi: 10.1007/s40263-021-00833-w. Epub 2021 Jun 23.

Longitudinal machine learning modeling of MS patient trajectories improves predictions of disability progression
Edward De Brouwer, Thijs Becker, Yves Moreau, Eva Kubala Havrdova, Maria Trojano, Sara Eichau, Serkan Ozakbas, Marco Onofrj, Pierre Grammond, Jens Kuhle, Ludwig Kappos, Patrizia Sola, Elisabetta Cartechini, Jeannette Lechner-Scott, Raed Alroughani, Oliver Gerlach, Tomas Kalincik, Franco Granella, Francois Grand'Maison, Roberto Bergamaschi, Maria José Sá, Bart Van Wijmeersch, Aysun Soysal, Jose Luis Sanchez-Menoyo, Claudio Solaro, Cavit Boz, Gerardo Iuliano, Katherine Buzzard, Eduardo Aguera-Morales, Murat Terzi, Tamara Castillo Trivio, Daniele Spitaleri, Vincent Van Pesch, Vahid Shaygannejad, Fraser Moore, Celia Oreja-Guevara, Davide Maimone, Riadh Gouider, Tunde Csepany, Cristina Ramo-Tello, Liesbet Peeters
Comput Methods Programs Biomed. 2021 Sep;208:106180. doi: 10.1016/j.cmpb.2021.106180. Epub 2021 May 18.

Update on the management of multiple sclerosis during the COVID-19 pandemic and post pandemic: An international consensus statement
Saúl Reyes, Anthony L Cunningham, Tomas Kalincik, Eva Kubala Havrdová, Noriko Isobe, Julia Pakpoor, Laura Airas, Reem F Bunyan, Anneke van der Walt, Jiwon Oh, Joela Mathews, Farrah J Mateen, Gavin Giovannoni
J Neuroimmunol. 2021 Aug 15;357:577627. doi: 10.1016/j.jneuroim.2021.577627. Epub 2021 Jun 7.

The effectiveness of natalizumab vs fingolimod-A comparison of international registry studies
Johanna B Andersen, Sifat Sharmin, Mathilde Lefort, Nils Koch-Henriksen, Finn Sellebjerg, Per Soelberg Sørensen, Claudia C Hilt Christensen, Peter V Rasmussen, Michael B Jensen, Jette L Frederiksen, Stephan Bramow, Henrik K Mathiesen, Karen I Schreiber, Dana Horakova, Eva K Havrdova, Raed Alroughani, Guillermo Izquierdo, Sara Eichau, Serkan Ozakbas, Francesco Patti, Marco Onofrj, Alessandra Lugaresi, Murat Terzi, Pierre Grammond, Francois Grand Maison, Bassem Yamout, Alexandre Prat, Marc Girard, Pierre Duquette, Cavit Boz, Maria Trojano, Pamela McCombe, Mark Slee, Jeannette Lechner-Scott, Recai Turkoglu, Patrizia Sola, Diana Ferraro, Franco Granella, Vahid Shaygannejad, Julie Prevost, Olga Skibina, Claudio Solaro, Rana Karabudak, Bart V Wijmeersch, Tunde Csepany, Daniele Spitaleri, Steve Vucic, Romain Casey, Marc Debouverie, Gilles Edan, Jonathan Ciron, Aurélie Ruet, Jérôme D Sèze, Elisabeth Maillart, Hélène Zephir, Pierre Labauge, Gilles Defer, Christine Lebrun, Thibault Moreau, Eric Berger, Pierre Clavelou, Jean Pelletier, Bruno Stankoff, Olivier Gout, Eric Thouvenot, Olivier Heinzlef, Abdullatif Al-Khedr, Bertrand Bourre, Olivier Casez, Philippe Cabre, Alexis Montcuquet, Abir Wahab, Jean-Philippe Camdessanché, Aude Marousset, Ivania Patry, Karolina Hankiewicz, Corinne Pottier, Nicolas Maubeuge, Céline Labeyrie, Chantal Nifle, Emmanuelle Leray, David A Laplaud, Helmut Butzkueven, Tomas Kalincik, Sandra Vukusic, Melinda Magyari
Mult Scler Relat Disord. 2021 Aug;53:103012. doi: 10.1016/j.msard.2021.103012. Epub 2021 May 8.

Lesser-Known Aspects of Deep Brain Stimulation for Parkinson's Disease: Programming Sessions, Hardware Surgeries, Residential Care Admissions, and Deaths
San San Xu, Charles B Malpas, Kristian J Bulluss, Hugh J McDermott, Tomas Kalincik, Wesley Thevathasan
Neuromodulation. 2022 Aug;25(6):836-845. doi: 10.1111/ner.13466. Epub 2022 Jun 14.

Natalizumab, Fingolimod and Dimethyl Fumarate Use and Pregnancy-Related Relapse and Disability in Women With Multiple Sclerosis
Wei Zhen Yeh, Putu Ayu Widyastuti, Anneke Van der Walt, Jim Stankovich, Eva Havrdova, Dana Horakova, Karolina Vodehnalova, Serkan Ozakbas, Sara Eichau, Pierre Duquette, Tomas Kalincik, Francesco Patti, Cavit Boz, Murat Terzi, Bassem I Yamout, Jeannette Lechner-Scott, Patrizia Sola, Olga G Skibina, Michael Barnett, Marco Onofrj, Maria José Sá, Pamela Ann McCombe, Pierre Grammond, Radek Ampapa, Francois Grand'Maison, Roberto Bergamaschi, Daniele L A Spitaleri, Vincent Van Pesch, Elisabetta Cartechini, Suzanne Hodgkinson, Aysun Soysal, Albert Saiz, Melissa Gresle, Tomas Uher, Davide Maimone, Recai Turkoglu, Raymond Mm Hupperts, Maria Pia Amato, Franco Granella, Celia Oreja-Guevara, Ayse Altintas, Richard A Macdonell, Tamara Castillo-Trivino, Helmut Butzkueven, Raed Alroughani, Vilija G Jokubaitis, MSBase Study Group
Neurology. 2021 Jun 15;96(24):e2989-e3002. doi: 10.1212/WNL.0000000000012084.

Predicting Infection Risk in Multiple Sclerosis Patients Treated with Ocrelizumab: A Retrospective Cohort Study
Nabil Seery, Sifat Sharmin, Vivien Li, Ai-Lan Nguyen, Claire Meaton, Roberts Atvars, Nicola Taylor, Kelsey Tunnell, John Carey, Mark P Marriott, Katherine A Buzzard, Izanne Roos, Chris Dwyer, Josephine Baker, Lisa Taylor, Kymble Spriggs, Trevor J Kilpatrick, Tomas Kalincik, Mastura Monif
CNS Drugs. 2021 Aug;35(8):907-918. doi: 10.1007/s40263-021-00810-3. Epub 2021 Apr 13.

Evolution of Brain Volume Loss Rates in Early Stages of Multiple Sclerosis
Tomas Uher, Jan Krasensky, Charles Malpas, Niels Bergsland, Michael G Dwyer, Eva Kubala Havrdova, Manuela Vaneckova, Dana Horakova, Robert Zivadinov, Tomas Kalincik
Neurol Neuroimmunol Neuroinflamm. 2021 Mar 16;8(3):e979. doi: 10.1212/NXI.0000000000000979. Print 2021 May.

The prevalence of epileptic seizures in multiple sclerosis in a large tertiary hospital in Australia
Suyi Ooi, Tomas Kalincik, Piero Perucca, Mastura Monif
Mult Scler J Exp Transl Clin. 2021 Feb 24;7(1):2055217321989767. doi: 10.1177/2055217321989767. eCollection 2021 Jan-Mar.

Prognostic value of acute cerebrospinal fluid abnormalities in antibody-positive autoimmune encephalitis
James Broadley, Robb Wesselingh, Udaya Seneviratne, Chris Kyndt, Paul Beech, Katherine Buzzard, Cassie Nesbitt, Wendyl D'souza, Amy Brodtmann, Richard Macdonell, Tomas Kalincik, Helmut Butzkueven, Terence J O'Brien, Mastura Monif, Australian Autoimmune Encephalitis Consortium
J Neuroimmunol. 2021 Apr 15;353:577508. doi: 10.1016/j.jneuroim.2021.577508. Epub 2021 Jan 30.

Peripheral Immune Cell Ratios and Clinical Outcomes in Seropositive Autoimmune Encephalitis: A Study by the Australian Autoimmune Encephalitis Consortium
James Broadley, Robb Wesselingh, Udaya Seneviratne, Chris Kyndt, Paul Beech, Katherine Buzzard, Cassie Nesbitt, Wendyl D'Souza, Amy Brodtmann, Tomas Kalincik, Helmut Butzkueven, Terence J O'Brien, Mastura Monif, Australian Autoimmune Encephalitis Consortium
Front Immunol. 2021 Jan 14;11:597858. doi: 10.3389/fimmu.2020.597858. eCollection 2020.

Lymphocyte reconstitution after DMF discontinuation in clinical trial and real-world patients with MS
Andrew Chan, John Rose, Enrique Alvarez, Amit Bar-Or, Helmut Butzkueven, Robert J Fox, Ralf Gold, Mark Gudesblatt, Jodi Haartsen, Tim Spelman, Katy Wright, Diana Ferraro, Patrizia Sola, Suzanne Hodgkinson, Tomas Kalincik, Jeannette Lechner-Scott, Christopher McGuigan, Karen Spach, Chongshu Chen, Sami Fam, Fan Wu, Catherine Miller
Neurol Clin Pract. 2020 Dec;10(6):510-519. doi: 10.1212/CPJ.0000000000000800.

Effect of lateral therapy switches to oral moderate-efficacy drugs in multiple sclerosis: a nationwide cohort study
Mathias Due Buron, Tomas Kalincik, Finn Sellebjerg, Per Soelberg Sørensen, Melinda Magyari
J Neurol Neurosurg Psychiatry. 2021 May;92(5):556-562. doi: 10.1136/jnnp-2020-324869. Epub 2021 Jan 12.